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Zebrafish

All articles tagged with #zebrafish

Lineage Guides Brain Assembly: A Simple Rule for Complex Neural Organization
science4 hours ago

Lineage Guides Brain Assembly: A Simple Rule for Complex Neural Organization

Researchers propose that brain cells determine their position not only via chemical signals but also through lineage, with descendants of the same progenitor tending to remain near one another. The lineage-based model of scalable positional information, tested in mouse brains and confirmed in zebrafish, suggests spatial organization can emerge from cell division/migration patterns, complementing chemical cues and potentially informing developmental biology and AI design.

via SciTechDaily|
#brain-development#lineage#neural-migration
Giant embryonic cells divide via a mechanical ratchet, not a closed actin ring
science4 days ago

Giant embryonic cells divide via a mechanical ratchet, not a closed actin ring

Researchers studying zebrafish embryos found that very large embryonic cells can divide without a fully closed actin contractile ring. Instead, they use a 'mechanical ratchet' system where cytoskeletal fibers and cycles of cytoplasmic stiffness—stabilized by microtubules—drive the contractile band inward step by step across several cell cycles, reshaping textbook views of cytokinesis in large eggs.

via ScienceDaily|
#cell-division#cytokinesis#cytoskeleton
Embryo Cell Division Driven by Mechanical Ratchet, Not a Full Contractile Ring
biology1 month ago

Embryo Cell Division Driven by Mechanical Ratchet, Not a Full Contractile Ring

Researchers from the Brugués group at TU Dresden report in Nature a new mechanism for early embryonic cell division in yolk-rich cells: a mechanical ratchet that drives division without a fully closed actin contractile ring. By showing microtubule asters stiffen the cytoplasm during interphase and the cytoplasm becomes more fluid in M-phase, they find the actin band can ingress across multiple cell cycles, anchored by microtubules and re-stabilized when the cytoplasm stiffens again. This challenges textbook models and may apply broadly to yolk-rich embryos across species.

via SciTechDaily|
#biology#cell-division#cytokinesis
Scientists Uncover How Fish Embryos Control Their Hatch Timing
science1 year ago

Scientists Uncover How Fish Embryos Control Their Hatch Timing

Israeli scientists have discovered the biological mechanism behind the 'hatching decision' in zebrafish, revealing that a transient brain structure releases a hormone, TRH, to trigger hatching. This hormone, known for thyroid regulation in humans, plays a different role in fish, controlling the timing of hatching based on environmental and developmental cues. The discovery could have implications for improving fish survival rates in aquaculture and understanding similar mechanisms in other species.

via Haaretz|
#aquaculture#fish#hatching
Revealing the Heart's Hidden Nervous System: A Mini-Brain Discovery
science1 year ago

Revealing the Heart's Hidden Nervous System: A Mini-Brain Discovery

New research from Karolinska Institutet and Columbia University reveals that the heart has its own complex nervous system, or "mini-brain," capable of independently regulating the heartbeat. This discovery, made through studies on zebrafish, challenges traditional views and could lead to new treatments for heart diseases like arrhythmias. The study highlights the heart's neural network's complexity and its potential interaction with the brain during stress or disease, offering new therapeutic targets.

via Neuroscience News|
#arrhythmias#heart#nervous-system
Zebrafish Brainstem Reveals Neural Pathways for Gaze and Memory
neuroscience1 year ago

Zebrafish Brainstem Reveals Neural Pathways for Gaze and Memory

Researchers at Weill Cornell Medicine used zebrafish larvae to study how brainstem neurons guide gaze and maintain short-term memory. By mapping neuronal circuits, they developed a computational model that accurately predicted network activity, offering insights into visual-motor systems and potential treatments for eye movement disorders. The study highlights the zebrafish's simple neural anatomy as a valuable model for understanding complex brain functions.

via Neuroscience News|
#brainstem#eye-movement#neural-circuits
"Brain Resets Connections in Early Sleep Stages"
science1 year ago

"Brain Resets Connections in Early Sleep Stages"

A study on zebrafish reveals that during the first half of sleep, the brain weakens new synaptic connections formed while awake, supporting the Synaptic Homeostasis Hypothesis. This process does not continue into the second half of the night, leaving questions about its purpose. The research highlights the importance of sleep in synaptic pruning, essential for cognitive performance and learning. Further studies are needed to understand the functions of different sleep stages and their impact on brain function.

via PsyPost|
#brain-function#neuroscience#science
Zebrafish Thrive as Shenzhou-18 Crew Completes First Spacewalk
sciencespace1 year ago

Zebrafish Thrive as Shenzhou-18 Crew Completes First Spacewalk

Four zebrafish sent to China's Tiangong space station are thriving after nearly a month in orbit, as part of a research project by the Chinese Academy of Sciences to study the effects of microgravity on vertebrates. The zebrafish, along with goldfish algae, are in good condition and are being observed for unusual behaviors and developmental changes. This research aims to understand the impact of space conditions on biological systems and has implications for long-duration space missions.

via Space.com|
#chinese-academy-of-sciences#microgravity#sciencespace
Chinese Astronauts Set Spacewalk Record on Tiangong Station
sciencespace1 year ago

Chinese Astronauts Set Spacewalk Record on Tiangong Station

Zebrafish sent to China's Tiangong space station are thriving in a self-sustaining aquatic ecosystem, part of a research project by the Chinese Academy of Sciences to study the effects of microgravity on vertebrates. This experiment, the first of its kind, aims to understand biological responses to space conditions and has implications for long-duration space missions.

via Yahoo! Voices|
#aquatic-research#chinese-space-program#microgravity
Shenzhou-18 Crew Advances Space Science with New Experiments
science-and-technology1 year ago

Shenzhou-18 Crew Advances Space Science with New Experiments

The Shenzhou-18 crew has been conducting various scientific experiments aboard the China Space Station since April 26, including life science and ecological studies with zebrafish and hornwort, and combustion research. They have observed abnormal behaviors in zebrafish due to microgravity and completed several technical tasks related to combustion and material experiments. The astronauts also perform regular exercises to counteract the physiological effects of microgravity.

via CGTN|
#china-space-station#microgravity#science-and-technology