Lineage Guides Brain Assembly: A Simple Rule for Complex Neural Organization
Researchers propose that brain cells determine their position not only via chemical signals but also through lineage, with descendants of the same progenitor tending to remain near one another. The lineage-based model of scalable positional information, tested in mouse brains and confirmed in zebrafish, suggests spatial organization can emerge from cell division/migration patterns, complementing chemical cues and potentially informing developmental biology and AI design.