The article presents a collection of fascinating facts across various scientific fields, highlighting discoveries about the brain's capacity, animal behaviors, medical innovations, and environmental phenomena, emphasizing how much there is still to learn about our world and ourselves.
Experts argue that the common advice of 'eat less, move more' is ineffective for long-term weight loss due to biological mechanisms like genetic predisposition and an 'obesity memory' that promote weight regain. They emphasize the importance of a holistic approach including diet, exercise, environmental changes, and possibly pharmacological interventions to address obesity more effectively.
USC researchers propose a new biological rule called 'selectively advantageous instability' (SAI), suggesting that instability in cellular components can be beneficial for genetic diversity and adaptability, but also contribute to aging and disease, challenging the traditional view that life favors stability.
The article highlights the weirdest scientific discoveries of 2025, including a carnivorous caterpillar, the possibility of Earth being in a cosmic void, unusual mummification methods, de-extinction efforts, a baby born from a 1994 embryo, innovative hair-based toothpaste, odd behaviors of orcas, fungi that can 'play' music, the impact of cat parasites on human behavior, perceptions of meat, and the discovery of a new color beyond human vision.
A large-scale genomic analysis revealed over 100,000 complete lytic phages embedded within bacterial genomes across diverse species and environments, challenging traditional phage classification and highlighting their potential in therapy and ecology. The study identified new phage lineages, expanded known groups, and found therapeutic phages naturally present in bacterial populations, suggesting a broader and more dynamic phage-bacteria interaction than previously understood.
Scientists have identified a lineage of archaea called Asgard archaea, specifically Hodarchaeales, as the common ancestor of all eukaryotic life, shedding light on the origins of complex cells in organisms like animals, plants, and fungi.
The study reveals that the nascent polypeptide-associated complex (NAC) plays a multifaceted role in protein synthesis by coordinating translation, folding, and targeting through sequence-specific interactions both inside and outside the ribosome tunnel, including an intra-tunnel sensing mechanism that influences translation kinetics and proteostasis.
A comprehensive study reveals that the longevity gap between women and men is rooted in biology and evolution, driven by genetic differences, reproductive strategies, and immune system variations, and persists across species and societies despite medical advances.
The study reveals that gene-specific selective sweeps are widespread across human gut microbiomes, driven by homologous recombination and horizontal gene transfer, with implications for understanding microbial adaptation to host diets and lifestyles worldwide.
The article reflects on a year of biology stories, exploring topics like cellular memory, Earth's deep time through evolution, the differences between AI and brains, the importance of curiosity in science, and the complexity of the sense of touch, highlighting recent research and philosophical questions in biology.
The article presents NeuMap, a comprehensive transcriptional map of neutrophil diversity across tissues, developmental stages, and disease conditions in mice and humans, revealing a limited set of conserved functional states or hubs that are dynamically regulated by signals and transcription factors, with implications for understanding neutrophil roles in health and disease.
The article uses molecular clock analyses of gene duplications to establish a timeline for eukaryotic cell evolution, suggesting that key features like the nucleus, cytoskeleton, and endomembrane system developed before mitochondrial endosymbiosis, with the divergence of eukaryotic lineages occurring around 1.8 billion years ago.
This article reviews the current research on mushroom-forming fungi, covering their biodiversity, genomics, ecological roles, and evolutionary history, highlighting recent discoveries in their symbiosis, decay mechanisms, and biogeography.
The study reveals that independent terrestrialization events in animals involved convergent genomic adaptations, including gene gains and losses related to osmoregulation, stress response, immunity, and sensory functions, with three major temporal windows identified during Earth's history, highlighting both predictable and lineage-specific evolutionary responses to land colonization.
Modern science shows that weight loss is hindered by our brain's biological defenses, which evolved to protect us from starvation and excess fat, making it difficult to lose weight and keep it off. These mechanisms, combined with societal factors and early-life influences, explain why dieting often fails, but advances in neuroscience and pharmacology offer new hope for effective treatments and prevention strategies.