All articles tagged with #immune system
Scientists at the University of Southampton developed a four-armed antibody that enhances T cell activation by clustering immune receptors, significantly boosting the immune response against cancer in laboratory tests, offering a promising new approach for cancer immunotherapy.
A comprehensive immune cell atlas from over 400 Chinese individuals reveals significant genetic and functional differences compared to European and Japanese populations, highlighting the importance of diverse data sets for personalized medicine and understanding immune variation across populations.
Scientists highlight Brazil's unique genetic diversity and long-lived individuals as key to understanding extreme human longevity, emphasizing the importance of studying admixed populations and resilience traits to uncover biological mechanisms that promote healthy aging.
Brazilian supercentenarians demonstrate exceptional immune resilience and unique genetic traits that may contribute to their extreme longevity, including strong antibody responses to COVID-19, unusual immune cells, and protective genetic variants, offering valuable insights into aging and disease resistance.
Many cancers can recur years after initial treatment due to dormant tumour cells that evade therapy and immune detection, with ongoing research aiming to understand and target these cells to prevent relapse.
Scientists have discovered that a small subset of maternal immune cells persist in offspring throughout life, actively maintaining immune tolerance to maternal cells and potentially influencing various health conditions, including autoimmune diseases, cancer, and neurological disorders.
Clementines are a low-calorie, nutrient-rich fruit in season from October to January, packed with vitamin C, antioxidants, and B vitamins that boost immunity, improve skin, support digestion, and enhance brain function. Regular consumption may reduce cold severity, promote collagen production, fight inflammation, and potentially lower dementia and depression risks, but caution is advised for those on certain medications due to compounds like furanocoumarins.
Tattoo inks contain complex chemicals, including potentially toxic metals and organic compounds, which can interact with the immune system, cause allergic reactions, and migrate to lymph nodes, raising concerns about long-term health effects. While generally considered safe, tattoos may influence immune responses and pose risks such as inflammation, allergic reactions, and possibly carcinogenic byproducts, especially with larger or more colorful tattoos. Better regulation and further research are needed to fully understand their health implications.
Scientists discovered that blocking the TAK1 protein in cancer cells slows tumor growth and enhances immune system attack in mice, suggesting a potential target for improving cancer immunotherapy, especially for melanoma, though further research is needed for human application.
Scientists have discovered that in colorectal cancer, two subtypes of regulatory T cells play opposing roles, with one subtype helping to restrain tumor growth and the other promoting it. This finding could lead to more targeted immunotherapies that selectively eliminate harmful Tregs, improving outcomes for patients.
Research shows that aging immune cells, specifically macrophages, can sustain a heightened inflammatory state through a pathway involving GDF3 protein, which may worsen responses to severe infections like sepsis; targeting this pathway could lead to new treatments for age-related inflammatory conditions.
A Tel Aviv University study reveals that melanoma cells release extracellular vesicles that disable immune cells, providing new insights that could lead to improved treatments for skin cancer.
Scientists at Northwestern Medicine have discovered that pancreatic tumors evade immune attack by using a sugar-based signal to hide, but they developed a monoclonal antibody that can restore immune responses in mice, offering hope for new treatments.
Researchers discovered that two types of brain immune cells, microglia, act as internal 'accelerators' and 'brakes' to regulate anxiety levels in mice, suggesting new avenues for understanding and treating anxiety disorders in humans.
Approximately 60% of the global population suffers from vitamin D deficiency, which plays a crucial role in immune response and vaccine effectiveness. Experts recommend daily supplementation, especially for older adults and those with darker skin, as dietary sources and sunlight are often insufficient to maintain optimal levels. Regular testing and consultation with healthcare providers are advised to determine appropriate vitamin D intake.