Tag

Serotonin

All articles tagged with #serotonin

health16 days ago•98 min saved

Sleep deprivation triggers brain–gut signals that damage gut stem cells

New research in Cell Stem Cell shows sleep deprivation in mice activates a brain-to-gut signaling cascade via the vagus nerve, triggering a surge of serotonin in the gut that damages intestinal stem cells and impairs the gut’s regenerative capacity. The study links insomnia to gut dysfunction and suggests acetylcholine from the vagus nerve drives serotonin release, highlighting potential therapeutic targets to protect gut health in sleep-disordered individuals.

via Live Science|

#gut-stem-cells #health #inflammatory-bowel-disease

neuroscience1 month ago•6 min saved

Light-Activated Amino Acids Yield Psychedelic-Style Brain Drugs Without Hallucinations

UC Davis researchers developed a light-driven method that combines amino acids with tryptamine and, after UV exposure, reshapes them into new molecules that activate the serotonin 5-HT2A receptor and may offer psychedelic-like brain benefits without altering perception. In mice, the leading compound fully activated 5-HT2A but did not induce hallucinogenic behaviors (head-twitch responses), leading researchers to pursue further studies on how other serotonin receptors might modulate or suppress perceptual effects.

via SciTechDaily|

#5-ht2a-receptor #drug-discovery #neuroscience

health-and-nutrition3 months ago•6 min saved

High-fat diet disconnects gut-brain communication

A high-fat diet disrupts the gut-brain axis by increasing serotonin in the gut while depleting it in the brain, leading to inflammation, impaired mood, and metabolic issues, highlighting the importance of gut microbiome health for mental and physical well-being.

via PsyPost|

#cognitive-decline #gut-brain-axis #health-and-nutrition

health3 months ago•3 min saved

Scientists Reveal Serotonin's Potential Role in Cancer

Recent research reveals that serotonin, beyond its role in mood regulation, may influence cancer development by interacting with DNA and activating cancer-related genes. Scientists are exploring targeted epigenetic therapies and ways to modulate serotonin levels, such as using SSRIs, to potentially improve cancer treatment outcomes. Understanding serotonin's diverse functions could lead to more precise therapies in the future.

via The Conversation|

#cancer #dna-interaction #epigenetic-therapy

health4 months ago•2 min saved

Gut Microbes and Serotonin: New Hope for IBS and Pain Relief

Research from the University of Gothenburg shows that gut bacteria can produce serotonin, which may lead to new treatments for irritable bowel syndrome (IBS), as certain bacteria like Limosilactobacillus mucosae and Ligilactobacillus ruminis increase serotonin levels and improve gut function, offering hope for addressing IBS symptoms.

via Medical Xpress|

#gut-bacteria #health #ibs

health4 months ago•7 min saved

Brain Test May Predict Sexual Side Effects in Antidepressant Users

Early research suggests a brain test measuring serotonin levels via EEG could predict antidepressant-related sexual side effects, potentially allowing for more personalized depression treatment to minimize these issues.

via CNN|

#antidepressants #brain-test #eeg

health-and-wellness7 months ago•2 min saved

Eating Pasta Boosts Happiness, New Study Shows

A 2023 study by Italian scientists found that eating pasta triggers positive emotional responses similar to listening to favorite music or watching sports, due to its effect on endorphin and serotonin levels, making it a comfort food that can boost mood and reduce stress.

via Chowhound|

#carbohydrates #comfort-food #happiness

science7 months ago•5 min saved

Beyond Serotonin: The Comprehensive Brain Engagement of Psychedelics

A new study reveals that psychedelics like LSD, psilocybin, and mescaline interact with a wide range of neural receptors beyond just serotonin, engaging multiple pathways that may explain their complex effects and therapeutic potential. These compounds activate numerous serotonin, dopamine, and adrenergic receptors, stimulating diverse intracellular signaling pathways, which could allow for the development of targeted, non-hallucinogenic therapies for mental health conditions. The findings highlight the intricate pharmacology of psychedelics and their potential for precision medicine in neuropsychiatry.

via Neuroscience News|

#brain #psychedelics #receptors

science8 months ago•4 min saved

Serotonin Circuits Use Motion Cues to Control Behavior

Scientists discovered how serotonergic neurons in larval zebrafish process visual feedback related to movement, using a gating mechanism that opens after swimming to help the brain learn which actions lead to successful outcomes, providing insights into neuromodulation and potential implications for understanding mood disorders.

via Neuroscience News|

#behavior #neuromodulation #neuroscience

health-and-wellness9 months ago•1 min saved

Top foods to boost mood and reduce stress naturally

Certain foods can naturally boost mood by supporting the production of happy hormones like serotonin, dopamine, and endorphins, which regulate mood, motivation, and stress relief.

via Times of India|

#dopamine #endorphins #happy-hormones

health9 months ago•5 min saved

Intermittent Fasting Enhances Libido by Reducing Brain Serotonin

A study in Cell Metabolism found that intermittent fasting enhances sexual behavior in aging male mice by lowering brain serotonin levels through altered tryptophan metabolism, leading to increased reproductive success despite unchanged sperm and hormone levels.

via PsyPost|

#brain-chemistry #health #intermittent-fasting

health1 year ago•7 min saved

Revolutionary Gut-Targeted Antidepressants Show Promise for Mood Disorders

Research highlights the role of gut serotonin in mood regulation, suggesting gut-specific treatments for depression and anxiety could avoid systemic side effects. Animal studies showed increased gut serotonin improved mood without digestive issues, unlike traditional antidepressants. Human data indicated prenatal antidepressant exposure raises the risk of functional constipation in children, emphasizing the need for targeted therapies, especially during pregnancy.

via Neuroscience News|

#antidepressants #depression #gut-brain-connection

health1 year ago•5 min saved

Revolutionary Gut-Targeted Antidepressants Show Promise for Mental Health

A new study suggests that targeting antidepressants to gut cells may treat depression and anxiety more safely than traditional SSRIs, which can cause developmental issues in children when used during pregnancy. By increasing serotonin in the gut, researchers found reduced anxiety and depressive behaviors in mice without the side effects associated with SSRIs. This approach could offer a safer alternative for pregnant women, as it avoids exposing the fetus to potential risks linked to systemic SSRIs.

via SciTechDaily|

#antidepressants #gut-health #health

health1 year ago•5 min saved

Gut-Targeted Antidepressants: A New Frontier in Mental Health Treatment

Recent research suggests that targeting gut cells rather than brain cells with SSRIs could effectively treat depression and anxiety while minimizing side effects. The study, led by researchers from Columbia University and NYU, found that increasing serotonin signaling in the gut of mice improved mood without the usual side effects of systemic SSRIs. This approach could be particularly beneficial for pregnant individuals, as it avoids risks associated with traditional antidepressants. The findings highlight the significant role of the gut-brain connection in mood regulation.

via Earth.com|

#anxiety #depression #gut-brain-connection

health1 year ago•2 min saved

Ayahuasca: A Plant-Based Solution for Trauma and Fear

A comprehensive review of a decade's research highlights ayahuasca's potential in treating PTSD and anxiety disorders by influencing emotional processing and memory through serotonin receptors. The study, led by researchers at the University of São Paulo, underscores the need for more clinical trials to explore ayahuasca's therapeutic applications and safety considerations.

via SciTechDaily|

#anxiety #ayahuasca #health