All articles tagged with #rna
New experiments support the 'RNA world' hypothesis by demonstrating how RNA could have formed on early Earth, with borates playing a beneficial role in stabilizing RNA components, suggesting a plausible pathway for the origin of life around 4.3 billion years ago, possibly delivered by asteroid impacts.
Scientists have discovered that sunburn damages a protective protein called YTHDF2 in skin cells, leading to uncontrolled inflammation that can trigger skin cancer. The research highlights how UV exposure breaks down YTHDF2, allowing non-coding RNAs to activate immune pathways associated with cancer development, offering new avenues for prevention and treatment.
Scientists in Sweden successfully extracted and analyzed RNA from a 130-year-old preserved Tasmanian tiger (thylacine), marking a significant advancement in ancient DNA research by revealing gene activity, tissue-specific signals, and potential viral traces, thus providing deeper insights into extinct species' biology and gene regulation.
Scientists in Sweden successfully recovered and analyzed RNA from a 130-year-old preserved thylacine, providing insights into its gene activity, tissue types, and potential viral history, marking a significant advancement in paleotranscriptomics and extinct species research.
Chemist John Sutherland explains that life's origins are plausible through natural chemistry involving simple molecules like hydrogen cyanide, challenging the idea that life requires a miracle, and suggests that life could be common in the universe if the right chemical conditions are met.
Scientists at Hebrew University have developed a novel small molecule using RIBOTAC technology that selectively targets and destroys the cancer-associated RNA TERRA, slowing tumor growth and opening new avenues for RNA-based cancer therapies beyond traditional protein-focused drugs.
Chemists at UMass Amherst have developed iConRNA, a publicly available tool that offers an unprecedented view of RNA behavior inside cells, aiding in understanding cellular functions and disease mechanisms related to phase separation of biomolecules.
Scientists from University College London recreated a 4-billion-year-old chemical reaction in lab conditions mimicking early Earth, demonstrating how RNA and amino acids could naturally bind to form the precursors of proteins, shedding light on the origins of life and bridging metabolism and genetics.
Scientists have replicated a key step in the origin of life by demonstrating how RNA and amino acids could have naturally combined on early Earth, using simple chemistry and a high-energy mediator called thioester, providing insights into the molecular processes that led to the emergence of life.
Scientists have discovered a water-friendly chemical reaction that links RNA and amino acids under mild conditions, providing a plausible pathway for the formation of the first proteins on early Earth and bridging the gap between metabolism, genetic information, and protein building.
Scientists at UCL have demonstrated a chemical process that could have occurred on early Earth, linking amino acids to RNA in water under neutral pH, providing insights into the origin of protein synthesis and supporting theories about life's emergence involving RNA and thioesters.
Scientists have discovered a chemical reaction that may explain how RNA and amino acids linked on early Earth, providing insights into the origins of life by bridging theories of RNA and thioester worlds, and demonstrating a potential pathway for the formation of self-replicating molecules in primordial conditions.
Researchers discovered that our cells hide their own RNA from the immune system by coating it with sugars, preventing unnecessary immune responses and potentially informing treatments for autoimmune diseases like lupus.
Scientists at Scripps Research discovered that ribose, a sugar crucial for RNA, is naturally more efficient at attaching to phosphate than similar sugars, suggesting a chemical advantage that may have contributed to the emergence of life’s molecular building blocks on early Earth.
Researchers at the Medical University of South Carolina have discovered a genetic mechanism involving R-loops, RNA:DNA structures, that regulate behavioral adaptations to emotional experiences by activating genes like NPAS4. This mechanism, which can prevent maladaptive behaviors such as drug-seeking and stress-induced anhedonia in mice, highlights the potential for RNA-based therapies to treat psychiatric disorders linked to stress and substance use.