All articles tagged with #amino acids
Reducing dietary isoleucine, an essential amino acid, in mice extended their lifespan by up to 33%, improved health markers, and reduced age-related issues, suggesting potential anti-aging benefits for humans, though further research is needed.
Scientists at the University of Southern Denmark discovered that reducing the amino acids methionine and cysteine in mice's diets can mimic cold exposure, significantly increasing energy expenditure and fat burning, which could lead to new obesity treatments. However, further research is needed to confirm if these effects occur in humans.
Researchers have discovered that D-cysteine, a mirror form of the amino acid cysteine, selectively inhibits the growth of certain cancer cells by blocking a key mitochondrial enzyme, showing promise for targeted cancer therapies with minimal effects on healthy cells, as demonstrated in mouse models.
Scientists are revising their understanding of the emergence of genes and amino acids in early life, suggesting that the traditional model may underestimate the role of certain amino acids like tryptophan and the complexity of early genetic codes, which could have implications for searching for life on other planets like Saturn's moon Enceladus.
Scientists are reevaluating the order in which amino acids emerged in the origin of life, suggesting that early protolife may have included a broader range of amino acids than previously thought, which could reshape our understanding of life's beginnings on Earth and potentially elsewhere in the universe.
The article debunks common misconceptions about protein, explaining its role in the body, sources, and optimal intake, emphasizing that most people do not need excessive protein and that a diverse diet can provide all essential amino acids without relying solely on meat or supplements.
The article explores how amino acids (AAs) stabilize protein and colloidal dispersions by weakly interacting with particles, modulating their interactions and increasing stability. It presents experimental evidence showing AAs raise the second virial coefficient (B22), indicating enhanced repulsion, and develops a theoretical framework modeling proteins as patchy particles with adsorption sites blocked by AAs. The findings suggest AAs have a generic colloidal effect, influencing biological processes like phase separation and stress granule formation, and can improve pharmaceutical formulations, exemplified by increased insulin bioavailability with proline.
Scientists from University College London recreated a 4-billion-year-old chemical reaction in lab conditions mimicking early Earth, demonstrating how RNA and amino acids could naturally bind to form the precursors of proteins, shedding light on the origins of life and bridging metabolism and genetics.
Scientists discovered that glioblastoma brain tumors in mice grow more slowly when deprived of the amino acid serine, revealing a potential metabolic vulnerability that could be targeted for therapy. The tumors typically steal nutrients like serine from their environment to support rapid growth, but a serine-deficient diet slowed tumor progression and extended survival in mice, offering new hope for treatment strategies.
Scientists have replicated a key step in the origin of life by demonstrating how RNA and amino acids could have naturally combined on early Earth, using simple chemistry and a high-energy mediator called thioester, providing insights into the molecular processes that led to the emergence of life.
Scientists have discovered a water-friendly chemical reaction that links RNA and amino acids under mild conditions, providing a plausible pathway for the formation of the first proteins on early Earth and bridging the gap between metabolism, genetic information, and protein building.
Reducing intake of the amino acid isoleucine in mice extended their lifespan by up to 33%, improved health markers, and reduced frailty, suggesting potential anti-aging benefits for humans, though further research is needed.
Scientists at UCL have demonstrated a chemical process that could have occurred on early Earth, linking amino acids to RNA in water under neutral pH, providing insights into the origin of protein synthesis and supporting theories about life's emergence involving RNA and thioesters.
Scientists have discovered a chemical reaction that may explain how RNA and amino acids linked on early Earth, providing insights into the origins of life by bridging theories of RNA and thioester worlds, and demonstrating a potential pathway for the formation of self-replicating molecules in primordial conditions.
Protein is essential for health, supporting tissue repair, immune function, and hormone production. The recommended daily intake is 0.8 grams per kilogram of body weight, but needs vary based on age, activity, and health conditions. Consuming more than two grams per kilogram offers little benefit and is generally safe. The timing of protein intake is flexible, and both animal and plant sources can provide quality protein, with a varied diet being most beneficial.