Tag

Super Agers

All articles tagged with #super agers

Super agers keep generating young neurons into old age
neuroscience8 hours ago

Super agers keep generating young neurons into old age

New Nature study finds that older adults with healthy cognition, including 'super agers', continue to produce immature neurons in the hippocampus at higher levels than those with cognitive decline, suggesting persistent neurogenesis may support memory; the neuron fraction is tiny (~0.01%), and the small sample sizes mean results should be interpreted cautiously; researchers hope to harness this process to develop therapies that boost neurogenesis in aging and Alzheimer's.

Genetic edge helps super agers stay mentally sharp into their 80s
health-and-medicine1 month ago

Genetic edge helps super agers stay mentally sharp into their 80s

A Vanderbilt-led study of 18,080 participants finds that people over 80 with unusually strong memory (super agers) carry fewer APOE-ε4 Alzheimer’s risk genes and more APOE-ε2 protective variants than their peers. Super agers were 68% less likely to carry ε4 than 80+ individuals with Alzheimer's and 19% less likely than cognitively normal peers, while they were 28% more likely to carry ε2, and 103% more likely than those with Alzheimer’s dementia to have this protective variant. As the largest study of super agers to date, the findings suggest a genetic basis for exceptional cognitive aging and may guide future dementia resilience research.

Researchers uncover secrets behind super agers' exceptional memory in old age
health6 months ago

Researchers uncover secrets behind super agers' exceptional memory in old age

A 25-year study from Northwestern University found that 'super agers' over 80 maintain exceptional memory and brain structure similar to much younger individuals, with some brains showing resistance or resilience to Alzheimer's-related proteins. Factors like larger memory-related neurons and social behavior may contribute to their cognitive resilience, suggesting that cognitive decline is not an inevitable part of aging.

Top Tips and Foods to Reverse Biological Age and Age Gracefully
health7 months ago

Top Tips and Foods to Reverse Biological Age and Age Gracefully

Super agers are individuals over 80 who remain free of chronic diseases, and research suggests that lifestyle, immune system health, and early detection through biomarkers are key factors in achieving such longevity, rather than genetics alone. Advances in medical science now enable better prevention and personalized health strategies, but societal and systemic changes are needed to make these accessible to all.

Secrets to Aging Gracefully and Staying Healthy at Any Age
health-and-wellness8 months ago

Secrets to Aging Gracefully and Staying Healthy at Any Age

Eric Topol highlights that healthy aging is more influenced by lifestyle factors such as diet, exercise, social engagement, and sleep than genetics. He advocates for adopting a Mediterranean diet, regular exercise, moderate alcohol consumption, avoiding unnecessary medical tests and supplements, and leveraging emerging genetic and organ clock testing to extend health span. Topol emphasizes that early intervention and lifestyle modifications can significantly increase years lived in good health, and he discusses promising medical advances like GLP-1 drugs for disease prevention.

Cracking the Code: Unveiling the Secrets to a Long and Fulfilling Life
health2 years ago

Cracking the Code: Unveiling the Secrets to a Long and Fulfilling Life

Scientists are studying a 100-year-old woman named Dorothy Boucek, who is part of a group known as Super Agers, to uncover the secrets to her long and healthy life. Boucek attributes her longevity to a combination of factors, including a happy disposition, a healthy diet, regular exercise, and social engagement. Researchers at the Albert Einstein College of Medicine are studying Boucek's genetic makeup to understand how it contributes to her exceptional brain function and overall health. The goal is to identify longevity genes that could potentially be targeted with medication in the future to help people live longer and healthier lives.

"Arizona Woman Unveils Secrets to Longevity Under Scientific Scrutiny"
health-and-science2 years ago

"Arizona Woman Unveils Secrets to Longevity Under Scientific Scrutiny"

Scientists are studying 100-year-old Dorothy Boucek, a Super Ager with the brain function of someone decades younger, to uncover the secrets to her long and healthy life. Boucek attributes her longevity to a combination of factors, including a happy disposition, a healthy diet, regular exercise, and social engagement. Researchers at the Albert Einstein College of Medicine are conducting the Super Agers Family Study, aiming to enroll 10,000 individuals aged 95 and older, along with their family members, to investigate the genetic factors contributing to long and healthy lives. The study may lead to the development of future interventions, such as longevity-enhancing pills.

Uncovering the Secrets of Super-Agers: Potential Steps Revealed.
health2 years ago

Uncovering the Secrets of Super-Agers: Potential Steps Revealed.

Researchers at the University of Rochester have found that older adults whose brain performance improves when they combine a cognitive task with walking may be "super-agers" whose brain ages slower than their body. Brain flexibility is an indicator of brain health, and this research offers a potentially necessary component for tracking the health of an individual’s brain. The markers could be used to assess the degree of disease progression, to evaluate treatment outcomes, and potentially to identify people, pre-clinically, at high risk for developing aging-related or disease-related cognitive decline.