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Health Medical Research

All articles tagged with #health medical research

health-medical-research1 year ago•3 min saved

"Determined Father's Quest for Son's Cancer Cure"

Fernando Goldsztein, a father from Brazil, is leading fundraising efforts to find a breakthrough cure for his son Frederico's Medulloblastoma, the most common brain cancer in children. Teaming up with doctors at Children’s National Medical Center in Washington D.C., they have formed the Medulloblastoma Initiative to focus on developing better therapies for this deadly form of brain cancer. They are on the verge of two FDA approved treatments that could result in a cure and fewer side effects for children facing treatment, offering hope to the 500 families affected by this diagnosis each year.

via Fox News|

#brain-tumor #cancer #childhood-cancer

health-medical-research1 year ago•1 min saved

"Promising Blood Test for Early Pancreatic Cancer Detection"

A new blood test has shown promise in detecting early-stage pancreatic cancer with up to 97% accuracy by identifying a genetic "signature" of the disease through the presence of specific RNA particles and DNA markers. The test, which outperformed the established marker CA 19-9, detected 93% of pancreatic cancers in U.S. participants and showed potential for early-stage disease detection. While more research is needed for validation, the findings offer hope for improved early detection of this often fatal malignancy.

via Newsmax|

#blood-test #early-detection #genetic-signature

health-medical-research1 year ago•3 min saved

"Promising New Drug Shrinks Pancreatic Tumors by 70% in Preclinical Model"

An experimental drug has shown promising results in shrinking pancreatic tumors by up to 70% in lab studies, offering hope for a more effective treatment for the aggressive and deadly cancer. The drug targets genetic drivers of pancreatic ductal adenocarcinomas, with researchers observing tumor shrinkage in 7 out of 10 models. This breakthrough comes as pancreatic cancer, which affects 67,000 Americans annually, has a low survival rate and is often diagnosed at late stages. Clinical trials will be crucial in determining the drug's potential to change the standard of care for pancreatic cancer patients.

via Daily Mail|

#clinical-trials #experimental-drug #genetic-mutation

health-medical-research1 year ago•2 min saved

"Geneos' Personalized Cancer Vaccine Shrinks Liver Tumors in Positive Trial Results"

In a small trial, a personalized cancer vaccine developed by Geneos Therapeutics, combined with an immunotherapy drug, shrank liver tumors in nearly a third of patients with advanced liver cancer. The vaccine, based on mutations specific to each patient's tumor, aims to boost the immune system's ability to recognize and attack hard-to-treat cancers. The promising results suggest a step forward in effective cancer vaccines and may expand the types of cancers that such therapies can treat. Larger trials are being planned to confirm these findings.

via The Globe and Mail|

#cancer-vaccine #clinical-trial #geneos-therapeutics

health-medical-research1 year ago•2 min saved

"Promising Results: Geneos Cancer Vaccine Shrinks Liver Tumors in Small Trial"

In a small trial, nearly a third of advanced liver cancer patients who received a personalized vaccine developed by Geneos Therapeutics alongside an immunotherapy drug saw their tumors shrink, a response twice as high as with immunotherapy alone. The vaccine, based on mutations specific to each patient's tumor, aims to boost the immune system's ability to recognize and attack hard-to-treat cancers. The study suggests progress towards effective cancer vaccines and potential expansion to treat various cancer types, with promising results in combining customized vaccines with immunotherapy. Larger trials are being planned to confirm these findings.

via Yahoo Finance|

#cancer-vaccine #geneos-therapeutics #health-medical-research

health-medical-research1 year ago•2 min saved

"GLP-1 Diabetes Drug Slows Parkinson's Progression in Small Trial"

A small mid-stage trial has shown that the diabetes drug lixisenatide, similar to Ozempic, helped slow the progression of motor disability in patients with early-stage Parkinson's disease. The drug, made by Sanofi, demonstrated potential in mitigating symptoms such as tremors and stiffness, but was also associated with an increased risk of gastrointestinal side effects. Larger and longer studies are needed to fully determine the efficacy and safety of this treatment for Parkinson's disease.

via CNBC|

#diabetes-drug #health-medical-research #lixisenatide

health-medical-research1 year ago•0 min saved

"GLP-1 Diabetes Drug Shows Promise in Slowing Parkinson's Progression"

New data from a French academic trial published in the New England Journal of Medicine suggests the potential for treating Parkinson’s disease with a GLP-1 agonist, although the impact so far is modest and important questions remain. The study adds to the growing body of research indicating the potential of the GLP-1 drug class to treat a wide range of conditions beyond diabetes and obesity, including kidney and heart disease, sleep apnea, and depression.

via Endpoints News|

#eli-lilly #glp-1-agonist #health-medical-research

health-medical-research1 year ago•3 min saved

"Early Cancer Signs Detectable Years Before Symptoms, Reveals Pioneering Research"

The newly opened Early Cancer Institute at Cambridge University is focusing on detecting changes in cells years before they become tumors, aiming to revolutionize cancer treatment. The institute has received £11m in funding and is developing innovative tests, such as the cytosponge, to detect precancerous conditions early on. By repurposing blood samples, researchers have identified genetic changes that differentiate those who later develop blood cancer from those who do not, providing a long window of opportunity for intervention. The institute's strategy includes pinpointing those at risk of cancer, reducing cancer risks, and ensuring widely administered treatments.

via The Guardian|

#blood-samples #cambridge-university #cancer

health-medical-research1 year ago•2 min saved

"Breakthrough in Pancreatic Cancer Treatment: Chinese Scientists Uncover Promising Protein Markers"

Chinese scientists have identified two protein markers that may predict chemotherapy sensitivity in pancreatic cancer, a discovery that could improve overall survival rates for the disease, which currently has a low five-year survival rate. The study, involving over 1,000 patients, sequenced the proteome and transcriptome to construct a model for pancreatic cancer prognosis and identified the biomarkers NDUFB8 and CEMIP2. The findings are expected to usher in a new era of precision diagnosis and treatment for pancreatic cancer, which is often diagnosed at advanced stages, limiting treatment options.

via South China Morning Post|

#chemotherapy-sensitivity #chinese-scientists #health-medical-research

health-medical-research1 year ago•1 min saved

"Targeting Dormant Breast Cancer Cells to Prevent Relapse: New Research Findings"

A breakthrough in breast cancer research has uncovered how to target "hibernating" tumour cells, offering new hope for patients with oestrogen receptor-positive breast cancer. Scientists discovered that hormone therapies can trigger changes in some cells, causing them to lie dormant instead of dying off and leading to a relapse years later. Inhibiting the enzyme G9a prevented cancer cells from becoming dormant and killed the cells that were already hibernating, potentially paving the way for innovative treatments to prevent breast cancer from recurring.

via NDTV|

#breast-cancer #cancer-research #g9a-enzyme

health-medical-research1 year ago•1 min saved

"UK Scientists Develop Groundbreaking Lung Cancer Vaccine Using DNA Technology"

Scientists in the UK have been granted funding to develop the world's first lung cancer vaccine, called LungVax, using technology similar to the Oxford/AstraZeneca COVID vaccine. The vaccine aims to train the immune system to recognize and attack cancer cells, potentially saving thousands of lives. If successful, the project could lead to a significant advancement in preventing lung cancer, which is the leading cause of cancer death in the EU, with cigarette smoking being the largest risk factor.

via Euronews|

#cancer-research-uk #clinical-trial #health-medical-research

health-medical-research1 year ago•5 min saved

"UK Scientists Develop Groundbreaking Lung Cancer Vaccine Using DNA Technology"

Scientists in London and Oxford are developing a groundbreaking lung cancer vaccine, known as 'LungVax', which could prevent up to 90% of cases by training the immune system to recognize and attack early signs of the disease. The vaccine targets neoantigens on abnormal lung cells and has received funding for initial manufacturing and research. If successful, it will move into clinical trials and could offer a viable route to preventing some of the earliest stage cancers from emerging.

via Daily Mail|

#cancer-prevention #health-medical-research #immunotherapy

health-medical-research1 year ago•2 min saved

"Inflammation-Reducing Drug Ineffective for Dry Age-Related Macular Degeneration, NIH Trial Finds"

A phase II clinical study at the National Eye Institute (NEI) found that the drug minocycline, which reduces inflammation, did not slow vision loss or geographic atrophy expansion in people with dry age-related macular degeneration (AMD). The trial, led by Tiarnan Keenan, M.D., Ph.D., tested whether inhibiting microglia with minocycline might help slow geographic atrophy expansion and its corresponding vision loss, but found no difference in geographic atrophy expansion rate or vision loss with minocycline. The study was funded by the NEI Intramural Program and took place at the NIH Clinical Center.

via National Institutes of Health (NIH) (.gov)|

#amd #clinical-trial #health-medical-research

health-medical-research1 year ago•3 min saved

"CRISPR-Cas Gene Editing Shows Promise in Eliminating HIV from Cells"

Scientists have made a significant breakthrough in the search for an HIV cure by using "genetic scissors" to eliminate the virus from infected cells in the laboratory. This technique could potentially lead to a treatment that eliminates the need for lifelong antiviral medication. While the findings are promising, it is still premature to declare a functional HIV cure on the horizon, and significant work is needed to turn this proof of concept into a viable treatment. Other research has also shown promise in reversing HIV's ability to escape detection by the immune system.

via Daily Mail|

#antiretroviral-therapy #crispr #cure

health-medical-research1 year ago•3 min saved

"Zika Virus Vaccine Shows Promise in Fighting Brain Cancer"

Scientists have developed a weakened version of the Zika virus that shows potential as a treatment for brain cancer, particularly glioblastoma multiforme (GBM). In lab experiments, the virus targeted and killed off tumor cells while sparing healthy cells. This research represents a new approach to repurposing the Zika virus, which has been primarily known for causing severe congenital conditions in newborns. The team from Duke-NUS Medical School plans to further develop the virus as both a Zika vaccine and a potential cancer treatment for various types of cancers.

via Gizmodo|

#brain-cancer #cancer-treatment #duke-university