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Cancer Research

All articles tagged with #cancer research

Tiny Plastics Detected in 9 of 10 Prostate Tumors, NYU Study Finds
health5 days ago

Tiny Plastics Detected in 9 of 10 Prostate Tumors, NYU Study Finds

A pilot NYU Langone Health study found microplastic particles in 9 of 10 prostate tumor samples, with cancerous tissue averaging about 40 micrograms per gram versus 16 in healthy tissue (roughly 2.5x higher). The team took rigorous contamination precautions, including using nonplastic tools, and analyzed 12 common plastic molecules. While findings raise the possibility that microplastics could influence cancer risk via inflammation, researchers caution that the small sample size requires larger studies to confirm any causal role; results will be presented at the ASCO Genitourinary Cancers Symposium.

NSMF Blockade Points to New Route in Colorectal Cancer Therapy
health10 days ago

NSMF Blockade Points to New Route in Colorectal Cancer Therapy

South Korean researchers report that silencing NSMF, a regulator of replication stress in colorectal cancer, triggers irreversible aging in cancer cells and slows or halts tumor growth in mouse models, suggesting a potential new therapy that spares healthy tissue. Published in Nucleic Acids Research, the study highlights NSMF as a key driver of cancer cell replication under stress. With rising colorectal cancer rates in younger Americans and calls to lower screening ages, the findings underscore the push for targeted treatments and earlier detection.

Cats Mirror Human Breast Cancer, Paving Cross-Species Treatment Paths
science10 days ago

Cats Mirror Human Breast Cancer, Paving Cross-Species Treatment Paths

A Science study analyzing nearly 500 feline tumors from five countries across 13 cancer types finds genetic similarities with human cancers, notably FBXW7 mutations in feline mammary tumors that mirror aggressive human cases; two chemotherapy drugs show promise against these tumors in cats, suggesting a potential path for new treatments in humans and enabling faster veterinary testing—highlighting cats as a valuable model for cancer biology and shared environmental factors.

Bacteria-Derived Toxin Halts Colorectal Cancer Growth While Sparing Healthy Tissue
science29 days ago

Bacteria-Derived Toxin Halts Colorectal Cancer Growth While Sparing Healthy Tissue

Researchers report that MakA, a toxin from Vibrio cholerae, when delivered systemically, slows colorectal tumor growth in mice by increasing tumor cell death and reshaping the tumor's immune environment, with no observable harm to healthy tissue or organs, suggesting a tumor-targeted anti-cancer strategy that requires further clinical study.

Global Expert Alliance Sets Course to Accelerate Therapeutic Cancer Vaccines
health1 month ago

Global Expert Alliance Sets Course to Accelerate Therapeutic Cancer Vaccines

More than 50 leading cancer vaccine researchers convene a two-day global think tank—organized by the Cancer Vaccine Coalition and AACR—to align priorities and accelerate development and access to therapeutic cancer vaccines through practical strategies, AI-driven antigen prediction, and coordinated funding and regulatory pathways, with trials across glioblastoma, melanoma, pancreatic, breast, ovarian and liver cancers and support from HSBC Innovation Banking, Northwest Biotherapeutics, Pfizer, and Anixa Biosciences.

Cancer Gene Pioneer and HIV/AIDS Denialist Dies at 89
science1 month ago

Cancer Gene Pioneer and HIV/AIDS Denialist Dies at 89

Peter H. Duesberg, a celebrated cancer biologist who helped identify the Src oncogene and later argued that HIV does not cause AIDS, died Jan. 13 in Lafayette, California, at 89 from kidney failure. His work shaped early ideas about oncogenes and cancer genetics, but his AIDS-denial advocacy drew sharp criticism for influencing public health policy; he retired in 2022 and is survived by his wife and four children.

Twenty Years of Cancer Advances Raise U.S. Five-Year Survival to 70%
science1 month ago

Twenty Years of Cancer Advances Raise U.S. Five-Year Survival to 70%

A 75th American Cancer Society Cancer Statistics report shows the U.S. five-year cancer survival rate has risen to about 70% (7‑in‑10) thanks to earlier detection and new treatments like immune checkpoint therapy and CAR‑T cell therapy. Survival has improved across cancers (breast 92%, melanoma 95%, prostate 98%), with leukemia and non‑Hodgkin lymphoma up ~20% and 18% and pancreatic and liver cancers also rising (to 13% and 22%). Myeloma and lung cancer survival have climbed to 62% and 15–28%, while late-stage survival now averages 35% (up from 17%). The death rate has fallen about 34% since 1991, saving roughly 4.8 million lives by 2023 — achievements driven by diagnosis, screening, and innovative therapies rather than a cure.

New Blood Tests Improve Early Detection of Pancreatic Cancer
health2 months ago

New Blood Tests Improve Early Detection of Pancreatic Cancer

New blood tests like the Grail Galleri offer hope for early detection of pancreatic cancer, which is crucial as most cases are diagnosed late with poor survival rates. Early detection can significantly improve treatment outcomes, but current screening options are limited, and the disease remains deadly, especially in Ohio where incidence and mortality rates are high. Researchers emphasize the importance of clinical trials and awareness efforts to improve prognosis and develop better therapies.

Dad Fights to Save Son and Others from Rare Brain Tumor
health2 months ago

Dad Fights to Save Son and Others from Rare Brain Tumor

Fernando Goldsztein, whose son Frederico was diagnosed with medulloblastoma, a rare and aggressive childhood brain tumor, has dedicated his life to finding a cure by founding the Medulloblastoma Initiative, which has raised $13 million and is conducting clinical trials to develop new treatments, aiming to save not only his son but thousands of other children affected by this disease.