All articles tagged with #clinical trial
Originally Published 2 days ago — by ScienceDaily
Scientists at USC are testing a tiny stem cell-based retinal implant in a phase 2b clinical trial to potentially restore vision in patients with advanced dry age-related macular degeneration, building on earlier promising safety and efficacy results.
Originally Published 3 days ago — by Krystal Biotech, Inc
Krystal Biotech announced positive interim results from its Phase 1 trial of KB407, a gene therapy for cystic fibrosis, confirming successful lung delivery and expression of wild-type CFTR protein across diverse patients, paving the way for a larger, repeat-dosing study expected to start in 2026.
Originally Published 3 days ago — by Eli Lilly
Eli Lilly's Phase 3b trial shows that combining Taltz (ixekizumab) and Zepbound (tirzepatide) significantly improves outcomes in adults with psoriatic arthritis and obesity, meeting primary and secondary efficacy endpoints and suggesting a potential new integrated treatment approach.
Originally Published 12 days ago — by SciTechDaily
A redesigned CD40 antibody drug, tested in a small clinical trial, has shown promising results by shrinking or eliminating tumors in some patients with metastatic cancers, with fewer side effects than previous versions, and appears to activate a systemic immune response.
Originally Published 16 days ago — by CNBC
Johnson & Johnson has discontinued its mid-stage trial of the experimental eczema drug JNJ-5939 after it failed to meet efficacy goals, but remains committed to developing other treatments for atopic dermatitis.
Originally Published 16 days ago — by Johnson & Johnson
Johnson & Johnson announced that their Phase 2b DUPLEX-AD study for JNJ-5939 in treating moderate to severe atopic dermatitis was terminated early after not meeting efficacy criteria, though the drug was well tolerated. The company remains committed to developing new treatments for the high-need condition.
Originally Published 17 days ago — by Earth.com
Scientists developed a plant-based hair serum containing Centella asiatica extract, which showed a 25% increase in hair thickness in a short, 8-week trial, suggesting potential for hair regrowth, though further research is needed to confirm efficacy and safety.
Originally Published 19 days ago — by SciTechDaily
A large international clinical trial found that daily fish oil supplements significantly reduce serious heart and vascular complications in dialysis patients, lowering major cardiovascular events by 43%.
Originally Published 20 days ago — by ABC News
A new drug, tofersen, shows promise in slowing or reversing symptoms of a rare form of ALS by targeting the SOD1 mutation, with some patients experiencing significant improvements and reduced risk of death, marking a potential breakthrough in ALS treatment.
Originally Published 21 days ago — by Mad In America
A study published in JAMA Network Open found that minimal online interventions, including digital CBT delivered via a phone app, led to full remission of severe generalized anxiety disorder in a majority of participants, challenging the notion that intensive treatment is always necessary for severe anxiety. Both digital CBT and psychoeducation were effective, with digital CBT showing higher remission rates, and even less intensive approaches like psychoeducation significantly benefiting participants.
Originally Published 21 days ago — by The Guardian
The NHS is launching a trial of Dialive, a device that cleans blood in patients with severe liver failure (ACLF), aiming to improve survival rates and potentially replace liver transplants, with promising early results and global significance.
Originally Published 22 days ago — by SciTechDaily
Researchers at USC are conducting a phase 2b clinical trial to test a stem cell-derived retinal implant aimed at reversing damage caused by dry age-related macular degeneration, potentially restoring vision in affected patients.
Originally Published 24 days ago — by ScienceAlert
A small Brazilian study found that microdoses of cannabis extract may help stabilize cognitive decline in patients with mild Alzheimer's disease, showing potential for a new therapeutic approach without psychoactive effects. Further research with larger samples is needed to confirm these findings.
Originally Published 25 days ago — by SciTechDaily
A European clinical trial found that the drug sulthiame can significantly reduce breathing disruptions in sleep apnea patients, offering a potential alternative to masks like CPAP, with most side effects being mild and temporary.
Originally Published 25 days ago — by Insmed Incorporated Investor Relations
Insmed's Phase 2b trial of brensocatib in CRSsNP did not meet efficacy endpoints, leading to discontinuation of that program, but the company acquired a promising monoclonal antibody, INS1148, for respiratory and inflammatory diseases, expanding its pipeline.