All articles tagged with #immune cells
New research shows leftover fragments from SARS-CoV-2 form protein pieces that bind to curved membranes on immune cells, suppressing dendritic cells and T cells and potentially driving long-COVID; Omicron fragments appear less damaging to these cells, highlighting variant differences while underscoring ongoing COVID risks and the value of vaccination.
Researchers found that immune cells formed in inflamed psoriasis skin can migrate into the bloodstream and travel to joints, where they encounter fibroblasts and ignite inflammation leading to psoriatic arthritis. The study explains why only some psoriasis patients develop arthritis and suggests blood-d detectable migratory cells could serve as an early warning, with future therapies aiming to intercept these cells before joint damage occurs.
Single-cell methylome and chromatin-accessibility analysis across 171 PBMC samples shows that genetic variation and environmental exposures independently shape immune cell epigenomes, with exposure- and genotype-associated regions showing distinct genomic enrichments (eDMRs at enhancers, gDMRs in gene bodies); colocalization of meQTLs with disease GWAS signals provides cell-type-specific insights into how genetics and environment influence health and disease.
New research shows that immune cells shed a sugar-rich surface layer called glycocalyx to enter inflamed skin in psoriasis, challenging previous beliefs and opening new avenues for treatment targeting immune cell migration.
A recent study shows that regular orange juice consumption affects thousands of genes in immune cells, reducing inflammation, blood pressure, and insulin resistance, which may benefit long-term heart health.
New research indicates that tattoo ink rapidly moves into the lymphatic system, causing immune cell death and inflammation, which can affect vaccine responses and potentially increase risks of lymphoma and skin cancers, raising concerns about tattoo ink safety and regulation.
New research reveals that immune cells shed their glycocalyx layer to facilitate movement into tissues during inflammation, challenging previous beliefs that only blood vessel walls modify their glycocalyx, which could influence future treatments for inflammatory diseases like psoriasis.
A study in mice suggests that engineered 'young' immune cells can partly reverse Alzheimer's symptoms and improve brain health by reducing inflammation and supporting memory-related cells, although further research is needed to confirm effects in humans.
Researchers at Trinity College Dublin discovered that applying electrical currents to macrophages can reprogram them to reduce inflammation and promote faster healing, offering a promising new approach for treating injuries and inflammatory diseases.
Scientists at Cedars-Sinai developed lab-created young immune cells from human stem cells that reversed signs of aging and Alzheimer's in mice, showing potential for future human therapies to improve brain health and memory.
A study published in Nature shows that pregnancy and breastfeeding promote the accumulation of specialized immune cells called CD8+ T cells in the breast, which can reduce the risk of breast cancer and improve survival rates, with effects lasting for decades.
Research shows that breastfeeding leaves long-lasting immune cells in the breast, particularly CD8+ T-cells, which help protect against breast cancer, especially aggressive types like triple-negative breast cancer. These immune cells remain for decades and are associated with better outcomes, suggesting potential for new preventive strategies and therapies.
Scientists in the UK have developed a blood test analyzing epigenetic changes in immune cells that could potentially diagnose chronic fatigue syndrome (ME/CFS), offering hope for earlier and more accurate diagnosis, though further research is needed due to the small study size.
A study shows that Ocrevus rapidly depletes B-cells in MS patients and causes gradual changes in T-cells, including increased regulatory T-cells after six months, which may contribute to its long-term effectiveness.
Researchers discovered a new type of immune cell in the fat tissue of mice that appears to contribute to age-related chronic inflammation, or inflammageing, with variations observed between sexes and age groups, shedding light on immune system changes during aging.