A new study reveals that ADHD medications like methylphenidate primarily act on brain networks related to wakefulness and reward, rather than attention control, by enhancing arousal and motivation, and can mask sleep deprivation effects, challenging traditional views of how these drugs work.
A study found that oxytocin enhances creativity in approach-oriented individuals by improving brain network connectivity and cognitive flexibility, but has no effect on avoidance-oriented individuals, highlighting the role of personality in hormonal effects on higher-level thinking.
Neuroscientists have discovered a repeating, clock-like rhythm in the brain that organizes large-scale network activity, cycling through different cognitive functions every 300 to 1,000 milliseconds. This structured cycle may help coordinate mental processes such as attention, memory, and sensory processing, and varies with age, genetics, and behavior, offering new insights into brain organization and potential implications for cognitive health and disorders.
Researchers have developed a novel ultrasound device capable of simultaneously stimulating multiple precise points in the brain non-invasively, using low-intensity ultrasound to reduce risks and enable visualization of brain activity, with potential applications for treating neurological and psychiatric disorders.
Recent studies reveal structural brain differences in individuals with psychopathic traits, a potential evolutionary trait in sharks related to tonic immobility, and a correlation between high IQ and more accurate life predictions, suggesting cognitive and biological factors influence behavior and decision-making.
A study using neuroimaging has identified specific brain regions with reduced volume associated with antisocial traits in individuals with psychopathy, highlighting a neurobiological link between brain structure and antisocial behavior.
A study in rodents shows that psilocybin causes widespread reorganization of brain networks, disrupting normal communication patterns and creating a high-frequency connectivity state, with effects varying by dose and time, providing insights into the neural basis of the psychedelic experience.
A study from Washington University School of Medicine reveals that psilocybin, the active compound in magic mushrooms, temporarily disrupts brain networks involved in introspective thinking, with effects lasting for weeks. This increased brain flexibility could aid in treating mental health conditions like depression and PTSD, highlighting the potential for psilocybin-based therapies under medical supervision.
A review of neuroimaging studies reveals that internet addiction in adolescents disrupts brain networks responsible for attention, memory, coordination, and emotional processing, impacting mental health. The study highlights the need for more diverse research to fully understand these effects.
A new study using fMRI investigates the brain's mechanisms behind deep focus, finding that certain brain networks synchronize and desynchronize, affecting an individual's ability to maintain attention. The research suggests that low-frequency fluctuations in brain networks play a key role in regulating sustained attention, providing potential insights for improving cognitive function. The study's findings could lead to better strategies for enhancing focus and attention in various cognitive tasks.
Researchers have discovered the default mode network, a collection of brain areas that activate when the mind is at rest, offering insights into brain function outside of specific tasks. This network is involved in processes such as mind wandering, memory recall, envisioning the future, and processing language, and may contribute to constructing an internal narrative. Studies are exploring its interactions with other brain networks, such as the salience network, and its potential links to mental health disorders. The default mode network has prompted neuroscientists to consider the effects of interactions between brain networks and appreciate the brain's activity during inward-focused tasks.
Researchers have discovered that Alzheimer's-related changes in brain networks extend beyond memory and attention, impacting sensory and motor circuits. These findings challenge previous assumptions about Alzheimer's effects and suggest that early-stage Alzheimer's may exhibit broader cognitive impairment detectable during mild cognitive impairment, potentially offering new treatment targets. The research indicates that brain network dysfunction could be a valuable marker for Alzheimer's diagnosis and disease risk assessment.
A new study conducted by researchers at the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) suggests that a group of brain regions known as the "salience network" is uniquely activated when drugs are taken intravenously, but not when taken orally. The study found that drugs that enter the brain quickly, such as through injection or smoking, are more addictive than when taken orally, and this difference may be due to the activation of the salience network. Understanding the brain mechanisms underlying addiction is crucial for developing new therapies for substance use disorders and addressing the overdose crisis.
A new study published in Cerebral Cortex suggests that electric fields play a crucial role in coordinating brain circuits and networks involved in memory encoding. The study found that the electric field generated by the underlying electrical activity of neurons coordinated the information across key brain regions during working memory tasks. This electric field appeared to drive neural activity and influence the fluctuations of voltage across neurons' membranes. The findings could have implications for understanding brain-computer interfaces and developing treatments for mental health conditions by manipulating electrical fields to alter faulty circuits.
Researchers have identified specific brain network connections associated with anosognosia, a condition where patients are unaware of their neurological or psychiatric deficits. Using a technique called lesion network mapping, they identified separate networks linked to visual and motor anosognosia and a shared network responsible for awareness of these deficits. The shared network converged on the hippocampus and precuneus, both associated with memory. This is the first systematic analysis to highlight the role of the hippocampus in visual anosognosia.