All articles tagged with #cognitive impairment
A 2025 study suggests that having a sense of purpose in life is associated with a 28% reduced risk of developing dementia, likely due to healthier behaviors and improved mental and emotional well-being, though causality has not been established.
A study suggests that 'chemo brain', the cognitive difficulties following chemotherapy, may be caused by damage to the brain's lymphatic system, specifically the meningeal lymphatics, due to chemotherapy drugs like taxanes, which impair the brain's waste drainage and are linked to memory and behavioral changes.
Researchers led by Prof. Takuya Takahashi have discovered that increased AMPA receptor density in the brain correlates with cognitive impairment in Long COVID patients, providing a potential biomarker and target for treatment of brain fog associated with the condition.
Scientists have identified increased AMPA receptor levels as a biological basis for Long COVID brain fog, using advanced PET imaging to correlate receptor density with cognitive symptoms and inflammation, paving the way for new diagnostic and treatment options.
Consuming green tea regularly may help protect against cognitive decline and reduce white matter lesions in the brain of older adults, potentially lowering the risk of dementia and supporting brain health after age 60.
A large autopsy study found that consuming eight or more alcoholic drinks per week is associated with brain vessel damage and cognitive decline, highlighting the long-term risks of moderate to heavy drinking on brain health.
A UC Davis study found that having a strong sense of purpose reduces the risk of cognitive impairment and dementia by about 28%, with benefits seen across racial and genetic groups, suggesting that psychological well-being plays a vital role in healthy aging.
Research indicates that reduced lithium levels in the brain are associated with Alzheimer's disease and cognitive decline. In mouse models, low-dose lithium orotate reversed memory loss and decreased amyloid plaques and tau tangles, suggesting potential for lithium replacement therapy. Further clinical trials are planned to explore its safety and efficacy in humans.
A new three-minute EEG-based test called the Fastball EEG could enable early detection of Alzheimer's disease by measuring brain responses to images, potentially allowing for earlier intervention and better management of the disease.
A study of over 13,000 adults found that having a strong sense of purpose in life is linked to a 28% lower risk of developing dementia and delays its onset, with benefits seen across racial, ethnic, and genetic groups, suggesting that fostering purpose through relationships, goals, or activities may help maintain brain health with age.
Targeting the iron-associated protein Ftl1 in the brains of old mice improves age-related cognitive decline by restoring synaptic and metabolic functions, suggesting Ftl1 as a potential therapeutic target for cognitive aging.
A study published in Nature Neuroscience has established a causal link between mitochondrial dysfunction and cognitive symptoms in neurodegenerative diseases. Researchers developed a new tool to stimulate mitochondrial activity, which improved memory deficits in animal models, suggesting mitochondria as a potential therapeutic target for conditions like Alzheimer's disease.
A study in Australia found that fatigue, mobility issues, and cognitive impairment in MS patients generally do not hinder engagement in healthy lifestyle habits, although mobility difficulties may reduce physical activity over time. Maintaining healthy habits like diet, vitamin D, and exercise is associated with fewer symptoms and slower disease progression, emphasizing the importance of personalized support for lifestyle adherence in MS management.
The Alzheimer’s Association has released the first clinical guidelines for blood-based biomarker tests to diagnose Alzheimer’s disease, recommending tests with ≥ 90% sensitivity and specificity for replacing or triaging more invasive tests like PET scans or CSF analysis, aiming to improve early and accurate diagnosis while emphasizing the need for further research and validation.
Recent studies suggest that long-term or frequent use of gabapentin may be associated with an increased risk of dementia and mild cognitive impairment, especially in users aged 35-64. While not proving causation, these findings prompt a reevaluation of its long-term use, emphasizing the importance of consulting healthcare providers, exploring alternatives, and adopting lifestyle measures to protect brain health.