All articles tagged with #bacterial infections
A Washington Post Well+Being article explains that urinary tract infections are usually caused by bacteria, most often E. coli, and that research suggests these bacteria may originate from meat in some cases. The piece emphasizes food-safety practices and proper meat handling/cooking as potential ways to reduce risk, noting that this link may influence those with recurrent UTIs.
DNA analysis of soldiers' remains from Napoleon's 1812 retreat reveals that bacterial diseases like typhus and trench fever contributed to the army's demise, adding complexity to historical understanding of the event.
The WHO reports a sharp global increase in antibiotic-resistant infections, especially in low and middle-income countries, with one in six bacterial infections showing resistance in 2023, raising concerns about limited treatment options and rising deaths from drug-resistant bacteria.
A new study suggests that bacteria from the mouth, particularly Streptococcus viridans, may trigger heart attacks by contributing to inflammation and plaque rupture in arteries, highlighting the importance of oral health and infection prevention in cardiovascular risk management.
Researchers have developed a swarm of magnetically guided micro-robots that can be injected into the sinuses to create on-site bacteria-killing reactions, offering a potential non-invasive treatment for nasal congestion and infections, though it is still in animal testing stages and faces public acceptance hurdles.
Scientists at the University of Nottingham have developed surface patterns on plastics that prevent bacteria from forming biofilms, potentially reducing infections on medical devices like catheters and activating the immune system to clear bacteria, offering a promising alternative to antibiotics and helping to combat antimicrobial resistance.
Researchers have developed a modified version of the antibiotic darobactin, showing effectiveness against drug-resistant bacteria like E. coli in animal trials. This advancement, published in ACS Infectious Diseases, highlights the potential of darobactin D22 as a new treatment option against pathogens that evade current antibiotics. The study, conducted during World Antimicrobial Resistance Awareness Week, demonstrated promising results in zebrafish and mice, suggesting further development towards clinical trials.
Researchers have discovered that the antibiotic plectasin forms Velcro-like structures on bacterial cell surfaces, trapping crucial components and enhancing its effectiveness. This novel mechanism, detailed in a study published in Nature Microbiology, could guide the development of new antibiotics to combat antimicrobial resistance. The presence of calcium ions further boosts plectasin's antibacterial activity, offering new insights for future drug design.
The FDA has approved Zevtera (ceftobiprole medocaril sodium for injection) for the treatment of Staphylococcus aureus bloodstream infections, acute bacterial skin and skin structure infections, and community-acquired bacterial pneumonia in adults and pediatric patients. The antibiotic was found to be effective in clinical trials, with common side effects including nausea, diarrhea, and headache. However, patients with a history of severe hypersensitivity to ceftobiprole or cephalosporin antibacterial class should not use Zevtera. The approval was granted with Priority Review, Fast Track, and Qualified Infectious Disease Product designations for the specified indications.
The CDC has issued an alert to healthcare providers about a rise in bacterial infections, specifically a strain of meningococcal disease caused by Neisseria meningitidis serogroup Y, which has seen 140 reported cases in 2024 targeting adults aged 30 to 60. Those at higher risk include Black and African Americans or individuals with HIV. Symptoms of the disease include meningitis and bloodstream infection, with Virginia currently experiencing a statewide outbreak. Awareness of symptoms and prompt medical attention are crucial in addressing this concerning trend.
A highly virulent and infectious form of streptococcus pyogenes, causing severe and potentially deadly infections, is spreading at a record rate in Japan, with officials struggling to identify the cause of the epidemic. Experts link the fast spread of the disease to the lifting of COVID-19 restrictions, prompting concerns about people abandoning basic hygiene measures. The rare streptococcal toxic shock syndrome (STSS) can cause serious illnesses and even death, particularly in adults over 30, and is estimated to be fatal in about 30 percent of cases. Japan's Ministry of Health, Labour and Welfare recommends people to resume the hygiene level they had during the COVID-19 pandemic to stop the spread of strep A.
The CDC has reported that between 2015 and 2020, there were 214 outbreaks of intestinal diseases caused by pathogens such as E.coli, campylobacter, or shigella, with over 2,000 cases of illness linked to drinking water, 80% of which were associated with public water systems, raising concerns about the safety of tap water.
The CDC warns that deadly bacterial infections have been spreading through tap water, with 214 enteric disease outbreaks and over 2,000 illnesses linked to drinking water from 2015 to 2020. Legionella, a biofilm bacteria causing Legionnaires’ disease, was the most common culprit. While U.S. tap water is generally safe, it may not be the best choice for certain uses, such as in neti pots, CPAP machines, and humidifiers. Experts advise against using tap water for wound cleaning, contact lenses, and preparing infant formula, as it can pose health risks. Boiling water, using filters, and inspecting pipes can help ensure better water quality, and residents are encouraged to report any changes in water appearance, taste, or smell to their water utility.
A new study published in Scientific Reports reveals that ancient Scandinavian bodies dating back 6,000 years show evidence of deadly bacterial infections, including Y. pestis, the bacteria that causes the plague, making it the oldest case of the plague found in remains to date. The shift from nomadic to agricultural communities led to increased population density and interactions with livestock, resulting in infections from food, water, and close human contact. The presence of bacteria causing meningitis and gonorrhea reflects the cultural change as people became less nomadic and started living in larger communities at the end of the Stone Age.
Researchers at the University of Illinois Chicago and Harvard University have developed a new antibiotic, cresomycin, that effectively suppresses drug-resistant bacteria by evading their defenses. The antibiotic, described in Science, targets the ribosome and is designed to overcome common bacterial resistance mechanisms. In animal experiments, cresomycin protected against infections with multidrug-resistant strains of common disease-causing bacteria. The next step is to assess its effectiveness and safety in humans, highlighting the critical role of structural biology in designing the next generation of antibiotics.