Tag

Antimicrobial Resistance

All articles tagged with #antimicrobial resistance

health4 days ago•15 min saved

Dentists still prescribe millions of clindamycin despite life-threatening C. difficile risk

Dentists prescribed over 2.3 million clindamycin prescriptions last year despite a decades‑old black‑box warning for serious C. difficile infections, even as overall dental antibiotic use rose about 6% from 2020 to 2025. The investigation ties unnecessary dental antibiotic prescribing to higher C. difficile risk and antimicrobial resistance, highlighting how private dental practice has lagged in antibiotic stewardship and guideline updates, with the story of Dolores Owens illustrating the potential harms of such prescribing.

via CIDRAP|

#antibiotic-stewardship #antimicrobial-resistance #c-difficile

science11 days ago•4 min saved

Ancient ice harboring bacteria shows multi-drug resistance

Researchers analyzing Scărișoara Ice Cave in Romania isolated a 5,000-year-old Psychrobacter bacterium (SC65A.3) that is resistant to 10 modern antibiotics across 8 drug classes and carries over 100 resistance genes, highlighting natural antimicrobial resistance that predates modern medicine.

via Euronews.com|

#ancient-bacteria #antimicrobial-resistance #ice-cave

science29 days ago•36 min saved

Space Mutations Boost Phages in the Battle Against Superbugs

A UW–Madison-led study compared a E. coli–T7 phage clash on Earth and in microgravity aboard the ISS. In space, phages infect more slowly but still acquire mutations that improve their ability to bind bacterial receptors, while the bacteria develop space-specific defenses—demonstrating space-driven evolutionary paths that could inform phage-based strategies against drug‑resistant pathogens on Earth.

via Yahoo|

#antimicrobial-resistance #bacteriophage #evolution

science3 months ago•4 min saved

Scientists Discover Potent New Antibiotic Hidden in Plain Sight

Scientists have discovered a new, highly potent antibiotic called pre-methylenomycin C lactone within a well-studied bacterium, which is over 100 times more effective against resistant bacteria like MRSA and VRE, and shows no resistance development, offering a promising new approach to combat antimicrobial resistance.

via SciTechDaily|

#antibiotic #antimicrobial-resistance #drug-resistance

health4 months ago•4 min saved

Global Crisis in Antibiotic Resistance and Innovation

The article discusses the escalating crisis of antimicrobial resistance (AMR), highlighting the insufficient pipeline of new antibiotics, the rise of drug-resistant bacteria, and the challenges in reducing antibiotic use in humans and livestock, which threaten global health efforts to combat resistant infections.

via Nature|

#antimicrobial-resistance #bacteria #drug-development

health-and-science4 months ago•6 min saved

AI-Driven Discoveries in the Fight Against Superbugs

Dr. Fred Mutisya, a Kenyan medical doctor and AI innovator, developed antimicro.ai, an open-source AI tool to analyze data on antimicrobial resistance (AMR). His work aims to improve antibiotic use and combat AMR, which poses a significant global health threat. While successful in Europe, the tool has yet to be adopted widely in Kenya, highlighting challenges in local healthcare innovation adoption.

via Daily Nation|

#ai-innovation #antimicrobial-resistance #health-and-science

health4 months ago•2 min saved

AI-Driven Breakthroughs in Antibiotic Discovery and Resistance Combat

AI is being used to rapidly design thousands of potential antibiotics to combat rising antimicrobial resistance, with some candidates showing promise in early tests, but challenges remain in manufacturing and stability before they can be tested in humans.

via Nature|

#ai #antibiotics #antimicrobial-resistance

health5 months ago•2 min saved

CDC Warns of Rising 'Nightmare Bacteria' and Superbug Infections in the US

Cases of drug-resistant 'nightmare bacteria' in the U.S. have increased nearly 70% from 2019 to 2023, driven mainly by bacteria with the NDM gene, which are difficult to treat and may lead to community spread and more chronic infections, raising significant public health concerns.

via NBC News|

#antimicrobial-resistance #cdc-report #drug-resistant-bacteria

health5 months ago•78 min saved

Hospital-Specific Phage Cocktail Developed for Enterobacter Cloacae Infections

Researchers designed a hospital-specific phage cocktail, Entelli-02, targeting Enterobacter cloacae complex to combat antimicrobial resistance, demonstrating broad efficacy in vitro, in vivo, and on clinical isolates, with potential for rapid clinical deployment.

via Nature|

#antimicrobial-resistance #bacteriophage-cocktail #enterobacter-cloacae

health5 months ago•3 min saved

US Faces Rising Threat from Drug-Resistant 'Nightmare' Bacteria

Infection rates from drug-resistant 'nightmare bacteria' with the NDM gene have increased nearly 70% in the US from 2019 to 2023, driven by limited treatment options and increased antibiotic use during the COVID-19 pandemic, posing a significant public health threat.

via The Independent|

#antimicrobial-resistance #cdc-report #drug-resistant-bacteria

health5 months ago•3 min saved

US Sees Rise in 'Nightmare Bacteria' Cases

Infection rates from drug-resistant 'nightmare bacteria' in the US have increased nearly 70% from 2019 to 2023, driven mainly by bacteria with the NDM gene, which are difficult to treat and may lead to community spread and more chronic infections, highlighting a growing public health concern.

via 5 EYEWITNESS NEWS|

#antimicrobial-resistance #cdc-report #drug-resistant-bacteria

science5 months ago•4 min saved

Ancient Bacteriophages Offer New Hope Against Superbugs

Imperial College London researchers discovered how 'pirate phages' hijack other viruses to transfer genetic material between bacteria, potentially advancing new treatments for drug-resistant infections and enhancing rapid diagnostics. They found that cf-PICIs hijack tails from unrelated phages to broaden their host range, facilitating the spread of resistance traits. This understanding could lead to innovative therapies and diagnostic tools, with ongoing efforts to develop applications and validate AI-driven research acceleration.,

via Imperial College London|

#antimicrobial-resistance #bacteriophages #biomedical-research

health6 months ago•4 min saved

Scientists Advancing Toward Staphylococcus aureus Vaccine

Scientists in China are developing a new vaccine against drug-resistant Staphylococcus aureus by targeting a specific surface loop on the MntC protein, which is essential for the bacteria's survival, potentially overcoming past vaccine failures caused by the bacteria's presence as a common commensal organism.

via Medical Xpress|

#antimicrobial-resistance #epitope-targeting #health

health6 months ago•5 min saved

Bacteria Infecting Cattle Now Threatening Human Health

A recent study shows that Salmonella Dublin strains infecting cattle are genetically very similar to those infecting humans and environmental sources in the U.S., indicating active cross-transmission and the need for integrated control strategies across animal, human, and environmental health to prevent severe illness and antimicrobial resistance.

via Earth.com|

#antimicrobial-resistance #bacteria-transmission #health

health6 months ago•4 min saved

Many Americans Mistakenly Believe They're Allergic to Penicillin

Many Americans who believe they are allergic to penicillin are not actually allergic, which can lead to less effective and more expensive treatments. Proper testing, including skin tests or small dose challenges, can accurately determine true allergies, allowing for safer and more appropriate antibiotic use, and reducing antimicrobial resistance.

via ScienceAlert|

#allergy-testing #antibiotics #antimicrobial-resistance