All articles tagged with #spinal cord injury
Three patients allege that spinal cord stimulator implants at Nura Pain Clinic caused paralysis or serious injuries, leading to lawsuits accusing doctors of risky placement and inadequate warnings; a third patient has joined the suits as the clinic says it emphasizes informed consent while litigation unfolds, and FDA data show thousands of adverse events linked to these devices, including cases of paralysis.
Northwestern researchers grew 3-millimeter-wide human spinal cord organoids from iPSCs, injured them in two ways, and treated them with IKVAV-PA 'dancing' supramolecular peptides that form a scaffold and promote axon regrowth. The treated tissues showed reduced glial scar and inflammation and enhanced neurite growth, aligning with prior mouse data and suggesting potential for human therapies—though clinical use is years away. The work was published in Nature Biomedical Engineering.
Scientists at Cedars-Sinai discovered a new role for astrocytes, called lesion-remote astrocytes (LRAs), which communicate with immune cells to clear debris and promote repair in spinal cord injuries, potentially leading to new treatments for neurological diseases.
A study published in Neurology found that while neurological recovery after spinal cord injury is similar across ages, older adults, especially those over 70, experience significantly less improvement in daily functioning and mobility, highlighting the need for age-specific rehabilitation approaches.
Michaela Benthaus, a German aerospace engineer and wheelchair user, became the first person with a disability to travel past the Kármán Line aboard a Blue Origin New Shepard capsule, experiencing microgravity and inspiring others with her journey.
A Pennsylvania man with a spinal cord injury has experienced significant improvement in mobility after receiving an experimental drug in a clinical trial, raising hope for future treatments for similar injuries.
Researchers at UCSD have identified the existing drug Thiorphan as a potential treatment to regenerate nerve cells in the spinal cord, showing promising results in animal models and human neuron studies, which could lead to new therapies for paralysis in the future.
Researchers identified thiorphan as a promising drug to promote neural regeneration and functional recovery after spinal cord injury by using a bioinformatics-driven pipeline, in vitro and in vivo testing, and validation in primate and human neurons, showing its potential for clinical translation.
Thomas (Tom) Charles Perley, a bright and independent man with Asperger’s Syndrome, passed away at 58 due to complications from a spinal cord injury sustained in a car accident. He was known for his intelligence, love of travel, music, and humor, and he cherished his independence and community involvement. His life was celebrated in a memorial service in Portland, Maine, and donations in his memory support Camp Nuhop and rehabilitation services.
Four-year-old Carter Grover, who previously recovered from infant paralysis caused by transverse myelitis, is now paralyzed from the neck down after a severe car crash that injured his spinal cord. Despite grim medical prognoses, his family and community are rallying to support his recovery and care, highlighting his resilience and the family's strength.
The article investigates the neuronal basis of autonomic dysreflexia after spinal cord injury, identifying specific neuronal subpopulations and their reorganization that trigger this life-threatening condition, and explores therapeutic strategies like electrical stimulation to modulate these neural circuits.
Brazilian researcher Tatiana Coelho de Sampaio and her team have developed polylaminin, a groundbreaking drug derived from placental protein, which has shown promise in regenerating the spinal cord and restoring movement in patients with paralysis, with successful experimental results and no reported side effects.
Scientists at the University of Minnesota have developed a novel method using 3D-printed scaffolds and stem cells to regenerate nerve fibers across severed spinal cords in rats, showing promising results for future paralysis treatments.
Researchers at the University of Minnesota have developed a 3D-printed scaffold populated with stem cells that successfully regrows nerve fibers and restores function in rats with severed spinal cords, offering promising potential for future spinal injury treatments.
Researchers at the University of Minnesota have developed a groundbreaking method using 3D-printed scaffolds and stem cells to repair spinal cord injuries in rats, leading to nerve regeneration and functional recovery, offering hope for future clinical applications.