All articles tagged with #neural repair
Researchers tested IKVAV-PA, a peptide-based nanomaterial, in a mouse model of acute ischemic stroke and found that systemic delivery allows the molecules to cross the blood-brain barrier and reduce brain tissue damage, inflammation, and harmful immune responses after reperfusion, indicating potential as an adjunct therapy—though human safety and long-term efficacy remain to be studied.
Researchers identified thiorphan as a promising drug to promote neural regeneration and functional recovery after spinal cord injury by using a bioinformatics-driven pipeline, in vitro and in vivo testing, and validation in primate and human neurons, showing its potential for clinical translation.
Two-dimensional (2D) nanomaterials, including graphene, layered double hydroxides, black phosphorous, transition metal carbides, and transition metal dichalcogenides, have unique structures and physicochemical properties that make them useful in neuroscience. They have been applied in regenerative medicine, tissue engineering, synaptic stimulation, neurodegenerative diseases, traumatic brain injury, and glioma. Graphene-based nanomaterials have significant electrical conductivity and good biocompatibility, making them excellent candidates for neural tissue engineering. 2D nanomaterials have also been used in the development of artificial synaptic devices and for early diagnosis and treatment of neurodegenerative diseases.