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Nitric Oxide

All articles tagged with #nitric oxide

science13 hours ago•7 min saved

Nitric Oxide Triggers TSC2 Loss, Overactivates mTOR in Autism

Excess nitric oxide can modify TSC2 via S-nitrosylation, marking it for destruction and removing the mTOR 'brake.' With TSC2 diminished, mTOR activity surges, disrupting neuronal signaling in autism models. Blocking NO signaling or engineering a NO-resistant TSC2 normalized mTOR and improved related cellular readouts in SHANK3 and CNTNAP2 mouse models, and clinical samples from children with SHANK3 mutations and idiopathic ASD showed reduced TSC2 and elevated mTOR, supporting a NO–TSC2–mTOR mechanism and suggesting nitric oxide inhibitors as a potential ASD therapy and biomarker target.

via Neuroscience News|

#autism #mtor #nitric-oxide

science-health1 month ago•6 min saved

Blocking SCoR2 Could Halt Fat Production and Lower Cholesterol

A Cleveland team identified SCoR2, an enzyme that removes nitric oxide from proteins controlling fat storage and production. In mice, inhibiting SCoR2 prevented weight gain, reduced liver damage, and lowered cholesterol, suggesting a first‑in‑class drug could treat obesity and cardiovascular disease, with clinical trials anticipated in about 18 months.

via SciTechDaily|

#cholesterol #lipogenesis #nitric-oxide

health4 months ago•3 min saved

Expert Tips on Exercise and Diet to Lower Blood Pressure Naturally

Aerobic exercise helps lower blood pressure by retraining blood vessels to stay relaxed and flexible, promoting better blood flow and reducing cardiovascular strain, while also reducing stress hormones and supporting overall heart health.

via Hindustan Times|

#aerobic-exercise #blood-pressure #health

health5 months ago•3 min saved

Daily Habits and Trends Impacting Health, Culture, and Entertainment

Certain everyday habits such as consuming refined sugar, processed starches, industrial seed oils, smoking, and using antibacterial mouthwash can reduce nitric oxide levels, impair blood vessel function, and increase the risk of heart attacks, highlighting the importance of healthy diet and lifestyle choices for cardiovascular health.

via The Times of India|

#cardiovascular-risk #health #heart-health

health9 months ago•2 min saved

Dentist Warns Daily Mouthwash Accelerates Aging

A dentist warns that daily use of alcohol-based mouthwash can harm beneficial oral bacteria, reducing nitric oxide production which is vital for blood pressure regulation and overall health. Overuse may also interfere with exercise benefits and is not recommended regularly, especially with alcohol-free variants that contain high essential oils.

via Hindustan Times|

#bacteria #daily-use #health

health1 year ago•3 min saved

Study Links Airborne Toxins to Autism Risk in High-Exposure Areas

New research suggests that air pollution inhaled by pregnant women may increase the risk of autism in genetically predisposed children. The study, led by Dr. Haitham Amal, highlights the role of pollutants like nitric oxide in potentially causing inflammation and altering brain development. With autism rates rising, the research underscores the importance of understanding environmental factors contributing to the condition. The study reviewed various pollutants, including particulate matter and nitrogen oxides, and found a significant correlation between exposure and autism risk.

via Daily Mail|

#air-pollution #autism #brain-development

health2 years ago•8 min saved

"Viagra's Potential Role in Preventing Alzheimer's Disease"

Professor Rob Galloway explores the potential link between Viagra and dementia prevention, highlighting the importance of addressing underlying health issues rather than relying solely on medication for erectile dysfunction. Research suggests that Viagra may reduce dementia risk by increasing blood flow to the brain, but its side effects warrant caution. The study also prompts consideration of alternative methods to boost nitric oxide levels, such as consuming nitrate-rich foods and antioxidants, as well as engaging in regular physical activity to support brain health.

via Daily Mail|

#antioxidants #dementia #erectile-dysfunction

science2 years ago•5 min saved

"Examining the Efficacy of Nasal Sprays in COVID Protection"

Nasal sprays containing iota-carrageenan or nitric oxide are being touted as potential tools for COVID prevention, with some studies showing promising results. However, these sprays are not approved by the FDA and lack sufficient clinical trial data to support their effectiveness. While some countries have approved certain nasal sprays, the slow pace of clinical trials and regulatory processes in the US has hindered their availability. Researchers are exploring innovative nasal treatments, such as sprays with ACE2 receptor-like filaments and molecules that inhibit viral binding, but more research is needed. Until then, wearing masks remains a crucial preventive measure.

via Slate|

#covid-prevention #fda-approval #iota-carrageenan

health2 years ago•2 min saved

"Breakthrough Discovery Unveils Promising Diabetes Treatment Options"

Scientists at Case Western Reserve University and University Hospitals in Cleveland have discovered a possible new cause of diabetes, identifying an enzyme called SNO-CoA-assisted nitrosylase (SCAN) that blocks insulin action by attaching nitric oxide to proteins. Increased SCAN activity was found in diabetic patients and mice, while mouse models without the SCAN enzyme were protected from diabetes. Lead researcher Jonathan Stamler suggests that blocking this enzyme could offer a new treatment for diabetes and potentially other diseases caused by excessive nitric oxide on proteins. This discovery opens up fresh pathways for treating diabetes and related conditions.

via The Mirror|

#diabetes #enzyme #health

health2 years ago•2 min saved

"Banana Spider Venom: A Potential Solution for Erectile Issues, Say Scientists"

Researchers in Brazil are studying the venom of the banana spider, known for causing painful and prolonged erections, to develop a synthetic molecule that could potentially treat erectile dysfunction. The spider's venom triggers the release of nitric oxide, which increases blood circulation and widens blood vessels, essential for erections. The research is considered promising, particularly for men who have had their prostate removed, as it could enable early cancer treatment. The medication is currently in the second phase of clinical trials before being approved for sale.

via Euronews|

#erectile-dysfunction #health #medical-treatment

health2 years ago•2 min saved

"Pharmacist reveals morning routine tweak for stronger erections in men"

Adding coffee to their morning routine could potentially help men with erectile dysfunction. Coffee contains caffeine, which stimulates the production of nitric oxide, a molecule that relaxes and widens blood vessels, facilitating blood flow to the penis and supporting erectile function. Coffee also has antioxidant and anti-inflammatory properties, which can benefit overall health and cardiovascular function. However, excessive caffeine intake should be avoided as it can lead to negative side effects. Erectile dysfunction can have both psychological and physical causes, and treatment may be necessary for underlying health conditions.

via The Sun|

#blood-flow #cardiovascular-health #coffee

health2 years ago•4 min saved

Autism linked to nitric oxide levels in brain neurons: Israeli study

Researchers at The Hebrew University of Jerusalem have found a link between the level of nitric oxide in brain neurons and autism spectrum disorder (ASD). The study investigated both mice and humans and found that higher levels of nitric oxide correlate with brain changes and higher levels of autistic behaviors. The findings could open the door to drugs to treat people with autism and other neurological conditions, but drug development is a long and challenging process that will take years at best.

via The Times of Israel|

#autism #brain-neurons #drug-development

health2 years ago•6 min saved

The Truth About Nitrates: Health Risks or Benefits?

Nitrates are compounds found in vegetables, meat, and drinking water. While some studies suggest that nitrates benefit cardiovascular health, others suggest they may increase cancer risk. Researchers conducted an analysis of studies investigating the benefits and risks of dietary nitrates and concluded that evidence is insufficient to say that nitrates in food and water are carcinogenic. Further research is needed to better understand these associations. Nitrates from vegetables that contain vitamin C or polyphenols may prevent the production of N-nitrosamines, meaning consumers can enjoy the nutrient’s benefits while avoiding its negative consequences.

via Medical News Today|

#cancer-risk #cardiovascular-health #dietary-intake

health-and-medicine2 years ago•2 min saved

Israeli Study Links Brain Nitric Oxide Levels to Autism and Reveals Potential Treatment Method

A new study has established a direct link between levels of nitric oxide (NO) in the brain and autism, offering insight into a previously undiscovered mechanism underlying the development of the condition. The team at the Hebrew University of Jerusalem demonstrated that behavioral and cellular indicators of autism were more apparent when levels of NO in the brains of mice were increased. The research team hopes that their work could open up the possibility for drug treatments that might help some autistic people with the challenges they face.

via IFLScience|

#autism #brain #health-and-medicine

health2 years ago•8 min saved

Israeli Scientists Discover Potential Method to Regulate Autism Symptoms.

Israeli scientists have identified a molecular mechanism that may be involved in autism, involving nitric oxide, a common molecule and neurotransmitter in the body that plays a key role in neuronal functions. The researchers found that increased nitric oxide in the brain might be one of the mechanisms that lead to autism. The findings are based on experiments on lab animals, clinical blood samples and human stem cells. The study provides a new direction for drug development for brain disorders, but the challenge is to create a new dynamic equilibrium of brain nitric oxide in autistic children without changing nitric oxide in other organs.

via Haaretz|

#autism #drug-development #health