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Meta Analysis

All articles tagged with #meta analysis

Fasting Generally Doesn’t Impair Adults’ Thinking, Large Review Finds
science13 days ago

Fasting Generally Doesn’t Impair Adults’ Thinking, Large Review Finds

A sweeping meta-analysis of 63 studies (3,484 participants) finds no meaningful difference in cognitive performance between fasted and fed healthy adults. Age matters (children fare worse when fasting); longer fasts may lessen performance gaps as ketones supply energy; testing later in the day and the presence of food cues can influence results; and the type of cognitive task matters. Overall, fasting appears compatible with maintained mental sharpness in adults, with caveats for kids and certain contexts, while metabolic benefits like autophagy and improved insulin sensitivity are noted but vary by individual.

via ScienceAlert|
#autophagy#cognitive-performance#fasting
Omega-3 Supplements Linked to Lower Aggression in Large Review
science20 days ago

Omega-3 Supplements Linked to Lower Aggression in Large Review

A 2024 meta-analysis of 29 randomized controlled trials (3,918 participants) found that omega-3 supplementation (fish oil) can reduce aggression by up to 28% in the short term across diverse ages and settings, with trials averaging 16 weeks and showing reductions in both reactive and proactive aggression; longer-term studies are needed to confirm and extend these findings.

via ScienceAlert|
#aggression#meta-analysis#nutrition
Big statin side-effect list largely not caused by the drugs, study finds
health22 days ago

Big statin side-effect list largely not caused by the drugs, study finds

A Lancet meta-analysis of 19 randomized trials involving about 124,000 participants over roughly 4.5 years finds that 62 of the 66 side-effects listed for statins have no solid evidence of being caused by the drugs; only four (liver test changes, minor liver abnormalities, urine changes, tissue swelling) have evidence supporting them. Overall, the risk of side-effects is very small and the cardiovascular benefits of statins—reducing heart attacks, strokes and cardiovascular deaths—greatly outweigh harms, prompting calls to update labeling to better reflect the evidence and reassure patients and doctors.

via The Guardian|
#cardiovascular#health#lancet
Vitamin D and Omega-3 Might Outperform Antidepressants in Depression Research
health28 days ago

Vitamin D and Omega-3 Might Outperform Antidepressants in Depression Research

Meta-analyses cited by a researcher suggest vitamin D and omega-3 supplements may reduce depressive symptoms more than common antidepressants: amitriptyline shows an effect size of about 0.417 vs placebo, omega-3 around 0.558 (1500 mg/day with at least 60% EPA), and vitamin D about 1.82 (5000 IU/day). These findings come from Cipriani 2018 (antidepressants), Sublette 2011+ (omega-3), and Ghaemi 2024 (vitamin D), but all estimates carry large uncertainty and official doses are blamed as “too low.” While supplements are cheap and generally safe, some caveats apply (kidney stones or blood thinners require medical advice). More research is needed, but the article argues trying these might be reasonable for some people under supervision.

via boingboing.net|
#antidepressants#depression#health
Yogurt's Bone Benefits Do Not Prevent Fractures, Study Finds
health4 months ago

Yogurt's Bone Benefits Do Not Prevent Fractures, Study Finds

A systematic review and meta-analysis found that while yogurt consumption shows a positive trend towards improving bone health markers, current evidence is insufficient to confirm significant benefits in fracture prevention or bone density improvements in adults, highlighting the need for high-quality randomized controlled trials with well-characterized yogurt products.

via News-Medical|
#bone-health#health#meta-analysis