Tag

Liver

All articles tagged with #liver

science8 days ago•66 min saved

Single-cell proteomics maps human liver zonation and its fragility in diseased tissue

Researchers used advanced scDVP to profile hundreds of hepatocytes from 18 people, building a high-resolution map of protein gradients along the liver's porto–central axis. They quantified ~2,500 proteins per cell, showed roughly half are zonated, and introduced gradient-based analysis to quantify zonation without binning. Cross-species comparison with mice revealed shared and human-specific zonation features; in tissues with disrupted architecture, zonation is broadly lost. The study delivers an open-access liver proteome resource and a framework applicable to spatial proteomics.

via Nature|

#liver #proteomics #science

biotechnology1 month ago•11 min saved

Lab-grown liver assembloids edge toward miniaturized human livers

Researchers combine multiple donor liver cell types to form in vitro liver assembloids that recapitulate periportal tissue, moving toward miniature human livers for faster drug testing and personalized therapies.

via Nature|

#bioengineering #biotechnology #in-vitro

health1 month ago•3 min saved

Detox myths debunked: your liver already cleanses you

A recent Strange Health episode scrutinizes detox fads like juice cleanses, charcoal pills, and foot patches, asking whether any detox is truly needed. Liver expert Trish Lalor says healthy people don’t require extreme interventions, since the liver, kidneys, and gut already detoxify the body around the clock. Real detox, she notes, is about hydration, fiber, rest, and moderation, not pricey supplements or gimmicks; many detox products are ineffective or potentially harmful and can drain your wallet. The discussion emphasizes skepticism toward online detox claims and clarifies what genuine bodily cleansing actually entails.

via ScienceAlert|

#detox #health #hydration

health2 months ago•4 min saved

Top 5 Hangover Myths Debunked by Experts

Most popular hangover remedies like 'hair of the dog,' greasy breakfasts, coffee, supplements, and exercise are ineffective because they don't address the body's actual process of metabolizing alcohol. Experts recommend hydration, rest, and balanced meals for recovery, and emphasize that the best way to avoid hangovers is to drink less and stay within safe limits.

via FOX 9 Minneapolis-St. Paul|

#alcohol #dehydration #hangover-myths

health2 months ago•8 min saved

Expert-Backed Habits for Effective Liver and Gut Detoxification

True detoxification of the liver and gut is achieved through lifestyle habits like a balanced diet low in sugars and saturated fats, regular physical activity, microbiome support with fiber and fermented foods, managing metabolic conditions, and considering genomic insights, rather than trendy juice cleanses or extreme detox diets.

via Times of India|

#detox #gut #health

health4 months ago•3 min saved

New Research Links Even Moderate Drinking to Increased Dementia Risk

Alcohol's impact on health varies across different ages, with increased sensitivity and long-term risks such as cognitive decline, hormonal imbalances, and cancer as we age. Reducing alcohol intake and taking breaks can significantly benefit health at any age.

via The Times|

#aging #alcohol #cancer

health5 months ago•2 min saved

Doctor Warns Against Certain Supplements and Cleanses

Medical experts warn against liver cleanses and supplements, as they lack scientific backing and can cause liver damage. Instead, maintaining a healthy diet like the Mediterranean diet, exercising regularly, and moderating alcohol intake are recommended to support liver health.

via TODAY.com|

#detox #diet #health

health7 months ago•3 min saved

Warning: Common Supplements May Cause Serious Organ Damage and Health Risks

Taking supplements without proper knowledge can silently harm the liver and kidneys, especially when combining multiple products, overusing certain nutrients, or ignoring pre-existing health conditions. It's crucial to check interactions, avoid excess intake, and consult healthcare professionals before starting any supplement regimen to prevent long-term organ damage.

via Times of India|

#health #health-risks #kidneys

health1 year ago•7 min saved

Fructose's Role in Cancer Growth: Liver's Lipid Conversion Under Scrutiny

Recent research from Washington University in St. Louis reveals that the liver converts dietary fructose into nutrients that promote tumor growth in cancers like melanoma, breast, and cervical cancer. This study suggests that high-fructose consumption, primarily from high-fructose corn syrup, indirectly fuels cancer by increasing lipid availability in the blood, which tumors use for growth. The findings highlight the potential for dietary strategies and therapeutic approaches targeting fructose metabolism to combat cancer.

via SciTechDaily|

#cancer #diet #fructose

health1 year ago•5 min saved

The Hidden Dangers of Alcohol: What Happens to Your Body

The article explains the effects of alcohol on the body, detailing how it is absorbed and processed, and the resulting hangover symptoms. Alcohol is quickly absorbed into the bloodstream, affecting mood and cognitive functions, and is metabolized by the liver at a constant rate. Hangovers result from dehydration, acetaldehyde buildup, and immune responses, causing headaches, nausea, and fatigue. Women and older individuals may experience more severe hangovers due to slower alcohol metabolism. Experts suggest moderation and hydration to minimize hangover effects.

via Daily Mail|

#alcohol #dehydration #hangover

science1 year ago•2 min saved

Unexpected Organ Revives Pig Brains Post-Cardiac Arrest

Chinese researchers at Sun Yat-sen University have partially restored brain function in pigs an hour after death by connecting their brains to functional livers, which produce protective molecules like ketone bodies. This innovative approach reduced brain damage markers and inflammation, suggesting the liver's potential role in extending the resuscitation window during cardiac arrest. While not yet applicable to humans, this breakthrough could revolutionize emergency medicine by improving survival rates and outcomes for cardiac arrest victims.

via The Daily Galaxy --Great Discoveries Channel|

#brain #cardiac-arrest #liver

health1 year ago•2 min saved

Unlocking the Link Between Body Clocks and Weight Gain

A study in mice shows that misalignment between the brain's and liver's circadian clocks, linked via the hepatic afferent vagal nerve (HVAN), can lead to disordered eating and weight gain. This suggests that targeting this neural pathway could be a potential treatment for obesity and metabolic disorders caused by circadian disruptions. The research highlights the importance of synchronizing the brain's light-based clock with the liver's food-based clock to maintain balanced metabolism.

via SciTechDaily|

#circadianrhythms #health #liver

health2 years ago•3 min saved

"The Impact of Alcohol Abstinence on Your Liver and Heart Health"

The liver, crucial for bodily processes, is susceptible to alcohol's effects, leading to fatty liver and potentially fatal cirrhosis. Giving up alcohol can lead to liver healing, with noticeable improvements in just a few weeks for fatty liver and within seven days for inflammation or mild scarring. Long-term abstinence can reduce the risk of worsening liver failure and death for heavy drinkers. Additionally, quitting alcohol has positive effects on sleep, brain function, blood pressure, and reduces the risk of various cancers and heart disease. However, it's important to seek medical advice when giving up alcohol, as sudden withdrawal can be dangerous for heavy drinkers.

via The Conversation|

#alcohol #cirrhosis #fatty-liver

health2 years ago•6 min saved

"The Transformative Effects of One Month of Sobriety on Your Body"

Giving up alcohol for a month can have numerous health benefits, even for lighter drinkers. The liver, in particular, has a remarkable regenerative capacity and can start to reverse damage caused by alcohol-related liver disease within weeks of abstinence. Other benefits include improvements in insulin resistance, blood pressure, weight, sleep, mood, and skin health. Alcohol disrupts the gut microbiome and damages the gut lining, but some of these effects can be reversed within a month. Additionally, abstaining from alcohol can provide insight into how alcohol consumption affects overall health and well-being, and it may lead to reduced alcohol consumption in the long term, resulting in significant health benefits.

via National Geographic|

#alcohol #drinking-habits #gut-microbiome

health2 years ago•5 min saved

"Massachusetts Man's Organ Superpower Leads to Remarkable Survival Story"

A Massachusetts man diagnosed with inoperable liver cancer found hope when a liver transplant specialist at Tufts Medical Center proposed a new treatment plan. The specialist utilized the liver's unique ability to regenerate and performed a procedure called double vein embolization, which allowed the healthy portion of the liver to regrow and eventually take over the organ's function. After the successful procedure, the tumor was safely removed, and the man is now feeling healthy and optimistic about the future.

via WCVB Boston|

#cancer #health #liver