Tag

Gut Microbiome

All articles tagged with #gut microbiome

science1 day ago•4 min saved

Virus Inside Gut Bacteria Linked to Colorectal Cancer, Study Finds

A Danish study identified a previously unknown bacteriophage inside the gut bacterium Bacteroides fragilis that is more commonly found in people with colorectal cancer. In a larger cohort, patients with cancer were about twice as likely to carry detectable levels of the phage, suggesting a virus–bacterium interaction may influence cancer risk and could inform future screening or treatment approaches. Causality has not been established, and more research is needed.

via ScienceAlert|

#bacteriophage #bacteroides-fragilis #colorectal-cancer

health-and-medicine3 days ago•9 min saved

Two Days of Oats Trim LDL Cholesterol by 10% and Rewire Gut Bacteria

A two-day, calorie-restricted, oat-dominant diet reduced LDL cholesterol by 10% in people with metabolic syndrome, with modest weight loss and lower blood pressure, and benefits persisted six weeks. The effect appears linked to changes in gut bacteria and their metabolites; a longer, less intensive oat plan yielded smaller gains.

via ScienceDaily|

#gut-microbiome #health-and-medicine #ldl-cholesterol

health3 days ago•19 min saved

Vagus nerve boom: can brain–body signaling actually curb inflammation?

The piece explains how the vagus nerve might regulate inflammation via bioelectric medicine, notes potential therapies like vagus nerve stimulation for conditions, but warns that hype from unverified experts and questionable devices can mislead, urging cautious, evidence-based approaches.

via The Independent|

#anxiety #gut-microbiome #health

science4 days ago•6 min saved

Childhood Junk Food Rewires Appetite Center, Gut Bacteria Offer Reset

In a mouse study, early-life exposure to a high-fat, high-sugar diet permanently shifts hypothalamic appetite pathways and adult feeding behavior even after weight normalizes; however, interventions targeting the gut microbiome—probiotic Bifidobacterium longum APC1472 or prebiotic fibers FOS/GOS—can restore brain–gut signaling and mitigate these long-term effects, with some sex-specific vulnerabilities observed.

via Neuroscience News|

#childhood-diet #gut-microbiome #hypothalamus

science6 days ago•4 min saved

Study links SNAC in oral semaglutide to gut microbiome shifts

A 21-day animal study suggests salcaprozate sodium (SNAC), the absorption aid in oral semaglutide, may alter the gut microbiome, lower short-chain fatty acids, raise inflammatory markers, increase liver weight, shrink the cecum, and reduce a brain-derived protein tied to cognitive impairment. While these findings raise questions about potential long-term effects of chronic SNAC exposure as oral obesity drugs become more common, researchers caution that results are not yet proven in humans and call for further investigation.

via SciTechDaily|

#gut-microbiome #inflammation #obesity

health6 days ago•260 min saved

Antibiotics Are the Biggest Gut Microbiome Disruptors, but Other Meds Matter

Gastroenterologists say antibiotics cause the most disruption to the gut microbiome, but other medications—including proton pump inhibitors, laxatives, NSAIDs, and certain cardiac drugs—can also alter gut bacteria, with some changes lasting years after stopping. Probiotics aren’t reliably regulated or proven to protect the microbiome, though Saccharomyces boulardii may reduce the risk of C. difficile diarrhea. If you must take such meds, focus on fiber-rich foods to support gut health and discuss qualquer protective steps with your doctor.

via AOL.com|

#antibiotics #gut-microbiome #health

health6 days ago•260 min saved

Antibiotics Are the Gut Microbiome’s Biggest Disruptor, Doctors Warn

Gastroenterologists warn antibiotics are the single biggest disruptor to the gut microbiome, though other meds like proton pump inhibitors, laxatives, NSAIDs, and certain cardiac drugs can also alter gut bacteria for years after use; probiotics are not reliably protective, though Saccharomyces boulardii may reduce the risk of C. difficile diarrhea; if you must take antibiotics, focus on fiber-rich foods to support gut health.

via AOL.com|

#antibiotics #cdiff #gut-microbiome

health7 days ago•3 min saved

VA Research Highlights: Agent Orange linked to acral melanoma, gut bacteria tied to Parkinson's, and a heart drug may curb opioid withdrawal

VA researchers publish three News Briefs: exposure to Agent Orange is linked to a higher risk of acral melanoma (a rare form of skin cancer); a gut bacterium, Desulfovibrio vulgaris, may drive Parkinson's disease by promoting alpha-synuclein buildup and affecting dopamine signaling; and acetazolamide, a heart disease drug, reversed opioid withdrawal–related brain changes in a mouse model, suggesting potential non-opioid treatments for substance-use disorders.

via VA News (.gov)|

#acral-melanoma #agent-orange #gut-microbiome

health7 days ago•18 min saved

Dairy’s double-edged effect on gut bacteria

A study analyzing wall-attached gut bacteria from colon biopsies finds dairy foods can have both positive and negative effects on the gut microbiome: higher total dairy and milk intake were associated with greater bacterial diversity and higher levels of beneficial microbes like Faecalibacterium and Akkermansia on the colon lining (with lactose likely driving part of this effect), while higher cheese intake correlated with lower levels of certain bacteria. Yogurt signals were inconclusive due to low consumption. Overall, dairy’s impact depends on the type of dairy, lactose content, fiber intake, and individual microbiome, and more diverse research is needed.

via Earth.com|

#cheese #dairy #gut-microbiome

health7 days ago•14 min saved

Emulsifiers in ultra-processed foods may disrupt your gut microbiome

New research links emulsifiers in ultra-processed foods to disruption of the gut microbiome: animal studies show emulsifiers push bacteria toward the gut lining, causing inflammation, and human data hint at increased risk of inflammatory diseases and diabetes with higher exposure; a small trial showed emulsifiers can reduce healthy gut microbes, while a Crohn's disease study suggested symptoms improved on a restricted-emulsifier diet. There is no clear public guidance yet, due to the complexity of additive mixtures ('cocktail effect'). A separate trial found that a low-UPF diet preserved greater gut microbe diversity than a high-UPF diet, reinforcing the value of cooking from fresh ingredients and moderating processed foods.

via BBC|

#dietary-additives #emulsifiers #gut-microbiome

science8 days ago•4 min saved

Hair Clues Point to Metal Imbalances in Parkinson's

In a small study of 60 Parkinson's patients and matched controls, researchers found distinctive metal profiles in hair—lower iron and copper with higher manganese and arsenic—raising the possibility of a non-invasive diagnostic biomarker. Mouse data linked hair iron deficiency to gut dysfunction, highlighting a gut–brain connection; further, larger studies are needed to confirm causality and mechanism and to validate hair metal patterns as a PD diagnostic tool.

via ScienceAlert|

#biomarkers #gut-microbiome #hair-biomarker

science8 days ago•43 min saved

Smart Underwear Tracks Gut Gases to Map Microbial Activity

University of Maryland researchers developed sensors in wearable underwear to measure intestinal hydrogen gas and establish baselines for gut microbial fermentation; early findings show healthy adults fart about 32 times per day (range 4–59), with volunteers being categorized as Zen Digesters, Hydrogen Hyperproducers, or Normal People for further study.

via Ground News|

#flatulence #gut-microbiome #hydrogen-gas

medical-science10 days ago•4 min saved

Western infants missing key gut microbe linked to health risks

A global atlas of gut bacteria shows that B. infantis, a microbe important for digesting foods and training the immune system, is largely absent in Western babies—about 98.6% lack it in the first two months in Europe and the US, versus ~29% in South Asia and Africa. The absence persists in many Western infants and could hinder immune development, potentially helping explain rising allergies and autoimmune diseases. Researchers suggest lifestyle factors such as antibiotic use, dietary shifts, reduced environmental exposure, and shorter or less exclusive breastfeeding may limit transfer of B. infantis from mother to child. The finding also questions the suitability of some commercial probiotic products, as they may not reflect regional strains, underscoring a need for tailored probiotic strategies and further study of microbiome-health links.

via Financial Times|

#b-infantis #breastfeeding #gut-microbiome

health12 days ago•6 min saved

Colorectal Cancer Surging in Young Adults Triggers Calls for Earlier Screening

Colorectal cancer is rising among people under 50, with lifestyle factors and gut microbiome imbalances suggested as contributors. Symptoms to watch for include blood in the stool, abdominal pain, and changes in bowel habits. Screening for average risk typically starts at age 45, with colonoscopy recommended for high-risk individuals, and early detection greatly improves survival. Lifestyle changes—regular exercise, a diet rich in fruit, vegetables and fiber, maintaining a healthy weight, and limiting alcohol and avoiding tobacco—along with discussing personal and family history with a healthcare provider can help lower risk.

via ScienceAlert|

#colorectal-cancer #early-onset-colorectal-cancer #gut-microbiome

science14 days ago•67 min saved

Host-gene signals point to gut physiology as main driver of microbiome diversity

A large GWAS of harmonized gut metagenomic data from 16,017 Swedish adults with replication in 12,652 Norwegians identifies host genetic variants linked to microbiome richness and 149 species; the strongest signal at OR51E1–OR51E2 suggests enteroendocrine fatty acid sensing shapes microbial communities, with additional loci near mucin genes and bile-acid pathways. Mendelian randomization links some taxa to LDL cholesterol and BMI-related traits, underscoring gastrointestinal physiology as a key driver of microbiome variation. Limitations include European-ancestry focus and challenges in pinpointing causal genes.

via Nature|

#enteroendocrine-cells #genome-wide-association-study #gut-microbiome