A high prevalence of fatty liver disease (84%) among Indian IT employees is linked to insulin resistance, high carbohydrate intake, and genetic factors, with sugar consumption—especially fructose—playing a key role in liver fat accumulation and inflammation, which can lead to serious liver and cardiovascular complications. Simply cutting calories or fat isn't enough; addressing insulin resistance and dietary habits is crucial.
Consuming fructose increases immune cell sensitivity to bacterial toxins, leading to heightened inflammation even in healthy individuals, which may have implications for metabolic health and disease risk.
Scientists have discovered that the enzyme ketohexokinase (KHK) plays a key role in alcohol addiction and liver damage by promoting fructose production during alcohol metabolism, and blocking this enzyme could lead to new treatments for these conditions.
A study shows that increasing dietary fiber, especially inulin-rich vegetables like garlic and onions, can prevent or reverse fatty liver disease caused by high fructose intake by altering gut bacteria, particularly Bacteroides acidifaciens, which helps break down fructose and protect the liver.
UC Irvine researchers found that consuming inulin, a vegetable-derived fiber, can reprogram gut bacteria to reduce fructose's harmful effects on the liver, potentially reversing fatty liver disease and insulin resistance, offering new avenues for nutrition-based disease prevention.
Recent research from Washington University in St. Louis reveals that the liver converts dietary fructose into nutrients that promote tumor growth in cancers like melanoma, breast, and cervical cancer. This study suggests that high-fructose consumption, primarily from high-fructose corn syrup, indirectly fuels cancer by increasing lipid availability in the blood, which tumors use for growth. The findings highlight the potential for dietary strategies and therapeutic approaches targeting fructose metabolism to combat cancer.
A study from Washington University in St. Louis suggests that high dietary fructose, particularly from processed foods containing high-fructose corn syrup, may promote cancer tumor growth in animal models. While fructose naturally found in fruits and vegetables is not harmful, excessive intake from processed foods can lead to increased lipid production, which may feed tumors. Experts emphasize the importance of understanding food labels and choosing natural sugars over processed ones to potentially reduce cancer risk.
New research suggests that fructose, a common sugar in American processed foods, may accelerate the growth of certain cancers, including skin, breast, and cervical tumors. The study found that fructose is converted by the liver into components that tumors use to grow, potentially making cancers more aggressive. Unlike natural fructose found in fruits, added fructose in foods like soda and salad dressing is prevalent in the US diet, with Americans consuming more than double the recommended amount of added sugar. Researchers advise cancer patients to avoid fructose when possible.
New research suggests that fructose, a sugar prevalent in high-fructose corn syrup, may accelerate cancer growth by being converted into lipids that cancer cells consume. Unlike glucose, fructose is metabolized only in the small intestine and liver, where it is transformed into compounds that support tumor growth. The study, published in Nature, highlights the potential impact of dietary fructose on cancer progression and suggests that reducing fructose intake could be beneficial for cancer patients. However, avoiding fructose is challenging due to its widespread presence in many foods.
A study published in Nature reveals that dietary fructose, commonly found in high-fructose corn syrup, promotes tumor growth in animal models by being converted into nutrients by the liver, rather than directly fueling tumors. This conversion increases circulating lipids, which cancer cells use to grow. The research suggests that reducing fructose intake could be beneficial for cancer patients and opens up potential therapeutic avenues targeting the metabolism of healthy cells to combat cancer. The study was funded by the National Institutes of Health.
Scientists propose a new theory called the "fructose survival hypothesis" which suggests that fructose consumption is the key driver of obesity. According to the theory, fructose depletes active energy and hinders appetite control, leading to an energy imbalance that promotes weight gain. This unifying perspective could guide more effective approaches to obesity prevention and management. The theory brings together various dietary hypotheses and suggests that fructose is the true driver behind obesity, while fatty foods become the major source of calories that drive weight gain. Further research is needed to fully validate this hypothesis.
Researchers have proposed a new hypothesis that fructose, a sugar found in many modern foods, may be the ultimate driver of obesity. Studies have shown that fructose suppresses the function of mitochondria, leading to a low-energy state that triggers hunger and thirst. This can result in chronic overeating and the storage of excess calories as fat. High-fructose corn syrup in processed foods is a common source of fructose, but other sugars and refined carbohydrates also generate fructose in the body. The researchers suggest avoiding sugary foods, watching salt intake, limiting red meat and alcohol consumption, and engaging in regular exercise to mitigate the effects of fructose. They are also working on developing a drug that inhibits fructose metabolism.
A new study proposes that fructose, a simple sugar found in many foods, may be the key driver of obesity. The authors suggest that fructose resets cell metabolism, increasing hunger and driving the desire for energy-rich foods, leading to weight gain. The study integrates existing obesity theories and suggests that obesity is a condition of low energy, marked by insufficient ATP due to the types and amounts of food consumed. Fructose suppresses the activity of mitochondria, reducing ATP levels and triggering biological responses such as increased energy intake, insulin resistance, and reduced resting metabolism. The consumption of processed foods and high fructose corn syrup exacerbates the problem. Moderating fructose consumption and adopting a diet rich in fiber, non-starchy vegetables, whole fruits, and legumes, while limiting high-fructose foods and drinks, can help with weight management and obesity prevention.
A major study led by medical doctor Richard Johnson suggests that fructose, a type of sugar found in fruit and added to sweeteners, may be the root cause of obesity. The study proposes that fructose triggers the urge to eat fattier foods, leading to overindulgence. The researchers argue that reducing both carbohydrates and fats together may be necessary for weight loss. Fructose metabolism causes a drop in ATP, signaling the body to seek more fuel and increasing hunger. This "fructose survival hypothesis" unifies various theories on obesity. Further research is needed to understand the mechanism fully.
A new study suggests that the primary driver of obesity is fructose, which is found in table sugar and high fructose corn syrup. The "fructose survival hypothesis" unifies various dietary theories of obesity by explaining how fructose lowers active energy in the body, leading to increased hunger and food intake. This theory views obesity as a low-energy state, where fructose redirects active energy replacement to fat storage. While further research is needed, this finding could potentially lead to more targeted preventions and management strategies for obesity and metabolic imbalances.
