All articles tagged with #down syndrome
Research shows that delivering the protein pleiotrophin (Ptn) to astrocytes in the brain can reverse neural connection and activity changes in mouse models of Down syndrome, suggesting potential for future therapies targeting brain wiring in neurodevelopmental disorders.
The study identifies HMGN1 as a dosage-sensitive gene on chromosome 21 that influences heart defects in Down syndrome, demonstrating that its increased expression reprograms heart cell identity and that reducing its dosage in mouse models rescues cardiac abnormalities.
Research by Neil Hunter's team uncovers how proteins safeguard chromosome crossovers during egg and sperm development, with implications for understanding fertility issues, miscarriages, and genetic conditions like Down syndrome, by studying the conserved process in yeast that mirrors human biology.
Scientists may have discovered a method to eliminate the chromosome linked to Down syndrome, raising hopes for potential prevention but also sparking ethical debates about eugenics and genetic modification.
Chris Burke, the first actor with Down Syndrome to star in a TV series, has defended comedian Shane Gillis over his controversial "Saturday Night Live" monologue, stating that people with Down Syndrome should not be excluded from being joked about by comedians. Burke believes that excluding people with Down Syndrome from being the subjects of jokes would be more offensive, and he sees some positives in Shane's monologue sparking a conversation about the condition.
A new study analyzing the DNA of almost 10,000 people from ancient and pre-modern societies has identified 6 cases of Down syndrome in past human populations, with one specimen dating back 5,500 years. The research aims to trace the origins of these individuals and understand how prehistoric societies treated people with Down syndrome and other rare conditions. The study, led by researchers at the Max Planck Institute for Evolutionary Anthropology, utilized a new statistical model to identify these cases and shed light on the treatment and integration of individuals with genetic conditions in ancient communities.
DNA analysis of ancient human remains dating back 5,000 years revealed six individuals with Down Syndrome, indicating that they were recognized and given noble burials in their respective communities. The research also uncovered an individual with Edwards Syndrome, a more severe genetic condition. The findings shed light on the care and appreciation these individuals received in ancient societies, providing insight into how ancient communities reacted to individuals with special needs.
Scientists have identified the genetic signature of Down syndrome in ancient bones of seven infants, some dating back 5,500 years, shedding light on how prehistoric societies may have treated individuals with rare conditions. The method, published in Nature Communications, may provide insight into the historical prevalence and treatment of Down syndrome, which is caused by an extra copy of chromosome 21 and can result in various health challenges. This discovery challenges the difficulty of confidently diagnosing ancient skeletons with Down syndrome due to its variable nature.
Researchers analyzing ancient DNA have identified six individuals from past societies with Down syndrome, dating back to between 5,000 and 2,500 years before present in Bronze Age sites in Greece and Bulgaria, and Iron Age sites in Spain. The individuals were found to have been cared for and appreciated as part of their ancient societies, with one individual also discovered to have Edwards Syndrome. The findings shed light on how ancient societies reacted to individuals with genetic conditions and may lead to further research in the future.
Andrea Fay Friedman, best known for her role on the TV show "Life Goes On," has passed away at the age of 53. Friedman, who had Down syndrome, died from complications of Alzheimer's disease. Her portrayal of a character with developmental disabilities on "Life Goes On" was groundbreaking and paved the way for more representation. Friedman also appeared on other shows such as "ER" and "Law and Order: SVU."
Andrea Fay Friedman, the actor with Down syndrome known for her role in the TV series "Life Goes On," has passed away at the age of 53 due to complications from Alzheimer's disease. Friedman's portrayal of a character with Down syndrome on the show was groundbreaking and helped provide a fully-rounded depiction of people with the syndrome. In addition to her acting career, Friedman was involved in advocacy work and worked with U.C.L.A.'s Pathway program for students with intellectual disabilities. She is survived by her father, sister, and nephews.
Andrea Fay Friedman, known for her groundbreaking role in the TV drama Life Goes On, has passed away at the age of 53. She died from complications of Alzheimer's disease, which is common in individuals with Down syndrome over the age of 50. Friedman, who had Down syndrome herself, used her platform to challenge stigmas and educate the world about people with the condition. She also appeared in other TV shows, including Family Guy, and worked as an assistant teacher at UCLA's Pathways program.
Andrea Fay Friedman, an actress known for her portrayals of characters with developmental disabilities, has passed away at the age of 53. She gained recognition for her role in the TV series "Life Goes On" and appeared in other popular shows such as "Baywatch" and "ER." Friedman, who had Down syndrome, referred to it as her "up syndrome." She died from complications of Alzheimer's disease, which is common in individuals with Down syndrome over the age of 50.
Families of individuals with Down syndrome are advocating for access to Alzheimer's trials and treatments, as Alzheimer's is the most common cause of death for people with Down syndrome. Advocacy groups are urging companies like Eisai and Eli Lilly to include people with Down syndrome in clinical trials for Alzheimer's treatments. However, neurologists caution against immediate use of these drugs in the Down syndrome population due to safety concerns. Advocacy groups are also seeking changes to Medicare policies to ensure reimbursement for treatments. While safety trials are being planned, it could be several years before results are available, prompting advocates to push for the removal of barriers to FDA-approved drugs.
Shively police have arrested 37-year-old Joseph Martin in connection to a fatal hit-and-run that killed 26-year-old Dimitric Dryden-Danzy, who was born with Down Syndrome and a heart condition. Martin is being charged with vehicular homicide, leaving the scene of an accident/failure to render aid, and no operator's license. A GoFundMe has been started to help Dryden-Danzy's family with funeral costs.