Hidden DNA Process Tied to Fertility, Miscarriage, and Down Syndrome Risks
TL;DR Summary
Research by Neil Hunter's team uncovers how proteins safeguard chromosome crossovers during egg and sperm development, with implications for understanding fertility issues, miscarriages, and genetic conditions like Down syndrome, by studying the conserved process in yeast that mirrors human biology.
- Miscarriages, down syndrome, and infertility all linked to this hidden DNA process ScienceDaily
- Holliday junction–ZMM protein feedback enables meiotic crossover assurance Nature
- A molecular zipper and a DNA link team up to protect fertility Phys.org
- Tiny DNA junctions provide feedback to control genetic crossovers MSN
- Scientists uncover hidden DNA process linked to infertility, miscarriage, and Down syndrome risks Asianet Newsable
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