Tag

Glycine

All articles tagged with #glycine

health2 years ago

Unlocking the Potential of Amino Acids for Depression Treatment

Researchers at the University of Florida have discovered a link between the amino acid glycine and depression through their research on brain cell signaling. They found that a receptor called GPR158, which binds to glycine, is connected to stress-induced depression. The discovery could lead to the development of new antidepressants. Depression affects millions of people, and while numerous medications treat depression, it can be hard to find the right one. More research is needed to target glycine specifically towards the mGlyR receptors in the brain.

health2 years ago

Unmasking the Power of Glycine in Treating Depression and Anxiety.

Scientists at the Wertheim UF Scripps Institute for Biomedical Innovation & Technology have discovered that the amino acid glycine can send a “slow-down” signal to the brain, potentially contributing to major depression, anxiety, and other mood disorders. The research focused on a receptor called GPR158, which, when bound to glycine, inhibits rather than activates cell activity. This receptor has been renamed mGlyR (metabotropic glycine receptor) and is being pursued as a drug target by startup company Blueshield Therapeutics. Further research is needed to understand the balance of mGlyR receptors and their effect on brain cell activity.

health2 years ago

Breakthrough Discovery Offers Hope for Major Depression Treatment.

Scientists at the Wertheim UF Scripps Institute for Biomedical Innovation & Technology have discovered that glycine, a common amino acid, can contribute to major depression, anxiety, and other mood disorders by delivering a "slow-down" signal to the brain. The discovery could lead to the development of new, faster-acting medications for hard-to-treat mood disorders. The researchers identified an orphan G protein-coupled receptor, GPR158, as a metabotropic glycine receptor (mGlyR) that mediates the slow neuromodulatory effects of glycine. Glycine signals through mGlyR to inhibit the production of the second messenger adenosine 3′,5′-monophosphate and regulates neuronal excitability in cortical neurons.

health2 years ago

Uncovering Triggers and Contributors to Major Depression

A study suggests that glycine, a naturally occurring amino acid found in many mood-boosting and sleep-enhancing supplements, may actually cause anxiety and major depression. Researchers found that glycine plays a role in the development of these diseases, and having too much of it could lead to the development of depression and anxiety. Glycine supplements are sold at stores such as Amazon and The Vitamin Shoppe, but the Florida researchers find that the chemical may instead be the cause of people's mental health issues — not a cure for it. The FDA warns that it is important to consult with a health care professional before using any dietary supplement.