A recent study on mice shows that just three days of binge drinking can cause rapid gut damage, including inflammation and increased intestinal permeability, which may lead to liver injury, highlighting early effects of alcohol on the gastrointestinal system.
Scientists from Ohio claim to have reversed Alzheimer's in mice using the compound P7C3-A20, which restores NAD+ levels and brain function, offering hope for future human treatments.
Reducing intake of the amino acid isoleucine in mice extended their lifespan by up to 33%, improved health markers, and reduced frailty, suggesting potential anti-aging benefits for humans, though further research is needed.
A groundbreaking study found that psilocybin not only extends lifespan in aging mice but also delays cellular aging in human cells, suggesting its potential as a treatment for age-related diseases and healthy aging. The research demonstrated increased survival rates, improved physical health, and cellular markers of reduced aging, though further studies are needed to confirm safety and efficacy in humans.
Research from Emory University shows that psilocybin, the active compound in psychedelic mushrooms, can extend cellular lifespan and improve health markers in mice, suggesting potential for anti-aging therapies in humans, though further studies are needed.
A lab study suggests that psilocybin, the active compound in magic mushrooms, may have anti-aging effects by extending cell lifespan, preserving telomere length, and improving health markers in older mice, though further research is needed to determine its applicability to humans.
A study suggests that psilocybin, the active compound in magic mushrooms, may extend cellular lifespan and improve survival rates in aged mice, potentially offering a new approach to anti-aging research, though human trials are still needed.
A preclinical study shows that psilocybin, derived from psychedelic mushrooms, significantly extends cellular lifespan in human cells and increases lifespan and health in aged mice, potentially offering a new approach to anti-aging therapies by reducing oxidative stress and preserving telomeres.
A study suggests that psilocybin, found in psychedelic mushrooms, may have antiaging effects by preserving telomere length and extending cellular and organismal lifespan, with promising results in human cells and aged mice, though further research is needed before clinical application.
A study published in Cell Metabolism reveals that reducing the intake of the essential amino acid isoleucine in middle-aged mice can extend their lifespan by up to 33% and improve various health metrics. The research suggests that similar dietary adjustments in humans might offer anti-aging benefits, though translating these findings to human diets is complex. The study highlights the potential of targeting specific amino acids for longevity interventions.
A new non-hormonal male contraceptive, CDD-2807, has shown promising results in mice, effectively reducing sperm activity and being reversible without significant side effects. Researchers at Baylor College of Medicine are optimistic about its potential and plan to test it in non-human primates.
Research in mice suggests that restricting the essential amino acid isoleucine in their diet can increase lifespan and healthspan, reduce frailty, and promote leanness and glycemic control. Male mice experienced a 33% increase in lifespan, while females had a 7% increase. The mice also showed improvements in various health measures. However, applying these findings to humans is complex, as diet is a complex chemical reaction and other dietary components may be involved. The study suggests potential anti-aging effects in humans through isoleucine restriction, but further research and potential interventions, such as an isoleucine-blocking drug, are needed.
A study in Sweden found that transplanting gut microbiota from individuals with social anxiety disorder into mice made the mice more sensitive to social fear, indicating a potential causal role of gut microbiota in the development of social anxiety disorder. The study revealed differences in gut microbiota composition and biochemical changes in mice that received microbiota from individuals with social anxiety disorder, leading to increased social fear responses. The findings highlight the potential influence of gut microbiota on mental health and suggest the microbiota-gut-brain axis as a target for developing novel therapeutics for social anxiety disorder.
Scientists have successfully reduced cholesterol levels in mice by using an alternative to genome editing that targets the epigenome, altering chemical tags on DNA without changing the DNA sequence. The study, published in Nature, demonstrates the potential for treating diseases by editing the epigenome, avoiding the risks associated with altering DNA. The findings have sparked excitement in the field of epigenetic editing, with several companies focusing on developing therapies, and a clinical trial underway for an epigenetic editor targeting a gene overactive in many cancers.
A new study led by Dr. Corina Amor Vegas at Cold Spring Harbor Laboratory describes a potential anti-aging therapy using CAR T cells, which are genetically engineered to target and destroy senescent cells linked to age-related health problems. In mice, a single injection of these senolytic CAR T cells in young adulthood slowed aging, improved metabolic profiles, and rejuvenated elderly mice. The treatment shows promise for addressing age-related diseases, but further research is needed to determine its long-term effects and potential side effects in humans.