All articles tagged with #autoimmune disease
A BuzzFeed list highlights 21 conditions many people dismiss as 'minor' but that profoundly affect daily life—from sleep disruption and chronic pain to migraines, GI issues, and autoimmune diseases—sharing Reddit stories to illuminate the real, lived impact.
Raynaud phenomenon occurs when small blood vessels overreact to cold or stress, causing color changes in fingers/toes (blue, white, red) and sometimes ulcers; primary Raynaud is common and usually harmless, while secondary Raynaud can accompany autoimmune diseases and be more severe. Diagnosis uses nailfold capillaroscopy and blood tests; treatments include off-label options like calcium channel blockers and, in severe cases, epoprostenol infusions. Prevention focuses on avoiding triggers, gradual warming, staying warm, stress reduction, and minimizing caffeine, nicotine, and other vasoconstrictors.
A large analysis of healthy human gut bacteria shows that about 80% of Pseudomonadota carry intact type III secretion systems, with over 90% possessing a host-directed secretion system. The researchers built a meta-interactome linking commensal effectors to human proteins, finding effector-target neighborhoods enriched for genetic variation tied to immune and metabolic diseases. Metagenomic data show effector enrichment in Crohn’s disease but depletion in ulcerative colitis. Functionally, commensal effectors can translocate into human cells and modulate NF-κB signaling and cytokine secretion in vitro, suggesting T3SS contribute to microbiome–host communication and may influence health and disease.
The piece argues Alzheimer's may be primarily an autoimmune disorder of the brain rather than just a brain disease, challenging the traditional beta-amyloid focus and the controversial aducanumab approval. It posits beta-amyloid may be part of the brain’s immune response that goes awry, driving dementia, while other theories (mitochondrial dysfunction, infections, metal handling) gain traction. With Alzheimer's affecting tens of millions worldwide, the article calls for new immune- and mechanism-based therapies and directions.
Groundbreaking research suggests that the Epstein-Barr virus (EBV), common in childhood, may be the trigger for lupus by causing immune cells to attack the body's tissues, potentially leading to new treatments and vaccine development.
The article shares Ruth Wilson's experience living with lupus, a complex autoimmune disease, highlighting her long diagnosis journey, daily struggles, treatment, and her efforts to support others and raise awareness about the disease.
The Stray Cats have canceled their upcoming 2025 tour due to frontman Brian Setzer's serious illness, which is related to an autoimmune disease that has affected his ability to play guitar. Refunds will be issued to fans, and the band had recently released new music after a six-year hiatus.
A Hertfordshire mother and biology teacher, Emily Henders, has become the first UK patient to receive a pioneering CAR T cell therapy in a clinical trial aimed at treating multiple sclerosis, a disease that causes immune system attacks on nerves. The experimental treatment, which depletes B cells to reset the immune system, offers hope for slowing or halting disease progression and could be a gamechanger if successful.
Researchers have developed a technology to reprogram rogue T cells into protective Treg cells, demonstrating targeted therapy for autoimmune diseases like pemphigus vulgaris, inflammatory bowel disease, and graft-versus-host disease in mouse models, potentially leading to safer, personalized treatments.
Lynn Milam's severe rheumatoid arthritis was dramatically improved by an FDA-approved nerve-stimulating implant that targets the vagus nerve, restoring her mobility and quality of life, and potentially offering a new treatment avenue for other autoimmune diseases.
The FDA has approved a device that uses electrical stimulation of the vagus nerve to reduce inflammation in rheumatoid arthritis patients, offering a new treatment option for those unresponsive to drugs, with promising results including pain relief and improved mobility.
Christina Applegate has opened up about how her MS diagnosis has deeply affected her 14-year-old daughter Sadie, who struggles with seeing her mother’s health decline and missing her previous self. The disease has caused emotional pain for both, with Sadie expressing her longing for her mom before MS, and Christina sharing how her condition has changed their lives and her daughter's perception of her. Despite the challenges, Sadie remains supportive, helping her mom with daily tasks and showing her love.
Tennis legend Monica Seles has revealed her diagnosis with myasthenia gravis, a chronic autoimmune neuromuscular disease, sharing her journey of adapting to the condition and raising awareness ahead of the U.S. Open.
Tennis legend Monica Seles has publicly shared her diagnosis of myasthenia gravis, a rare autoimmune neuromuscular disorder, to raise awareness and help others dealing with similar health challenges. She described her symptoms, the impact on her life, and her motivation to advocate for understanding and support for the disease.
Tennis legend Monica Seles has revealed her diagnosis of myasthenia gravis, a rare autoimmune neuromuscular disease, to raise awareness. The disease causes muscle weakness and fatigue, affecting her daily life, and has no cure but can be managed with treatment. Seles shared her experience ahead of the U.S. Open to educate others about the condition.