All articles tagged with #genome sequencing
A large genomic study links the blight-causing Phytophthora infestans to the Andes, resolving a long-standing debate about its birthplace and highlighting genomic-tracking tools and Andean wild potato resistance for predicting and combating future outbreaks.
A Scientific Reports study analyzing whole-genome data from 130 offspring of Chernobyl cleanup workers, 110 offspring of radar operators, and controls finds a higher count of clustered de novo mutations (cDNMs) in children of irradiated parents (average 2.65 per child in the Chernobyl group, 1.48 in the radar group, 0.88 in controls), with higher parental radiation dose associated with more cDNMs. Most cDNMs occur in non-coding DNA, suggesting minimal disease risk, and the overall risk of disease in offspring remains small. The study notes limitations, including historical exposure estimates and potential participation bias, and emphasizes a transgenerational effect of prolonged low-dose ionizing radiation.
Researchers analyzed tissue from a 14,000-year-old wolf pup found in Siberia and recovered the woolly rhinoceros genome from its stomach, revealing stable rhino genetics up to extinction and suggesting climate change, not hunting, as the primary driver of the woolly rhino’s disappearance.
In Siberian permafrost, scientists recovered a chunk of woolly rhinoceros tissue inside the stomach of one of two mummified Tumat wolf pups, enabling the first full genome of an Ice Age animal reconstructed from inside another Ice Age animal. The rhinoceros died about 14,400 years ago; its genome shows healthy genetic diversity up to near extinction, supporting climate change as the key driver of its demise rather than inbreeding. The finding highlights the value of preserved ancient DNA for understanding past ecosystems and informs conservation lessons for modern species facing warming and human pressures.
A new study sequencing the vampire squid genome reveals its position as a genomic 'living fossil' that links squids and octopuses, showing how chromosomal changes shaped cephalopod evolution and highlighting the vampire squid's retention of ancient traits.
Scientists sequenced the genome of the vampire squid, revealing it has retained many ancient, squid-like chromosomal features despite belonging to the octopus group, making it a 'living fossil' that offers insights into cephalopod evolution.
Scientists sequenced the largest cephalopod genome ever, revealing that the vampire squid, a living fossil, retains ancient genetic traits linking it to both squids and octopuses, providing insights into cephalopod evolution.
Hamilton Smith, a Nobel laureate and molecular biologist, co-discovered type II restriction enzymes that revolutionized DNA analysis, and later contributed to sequencing the first complete genome of a bacterium and the human genome, significantly advancing molecular biology and genomics.
Svante Pääbo, a pioneer in paleogenetics and Nobel laureate, has significantly advanced our understanding of human evolution by sequencing Neanderthal and Denisovan genomes, revealing interbreeding with modern humans, and exploring genetic traits inherited from these ancient relatives. His work suggests that modern humans absorbed Neanderthals rather than exterminated them, and highlights the influence of ancient DNA on present-day health and behavior. Pääbo also discusses the potential and limitations of reconstructing extinct species' genomes and the ethical considerations involved.
The Atlas blue butterfly has the highest number of chromosomes ever recorded in an animal, with 229 pairs, resulting from chromosomes splitting into smaller sections over three million years. This discovery provides insights into evolution, adaptation, and potential implications for human cancer research, as chromosomal rearrangements are also seen in cancer cells.
This study uses high-resolution haplotype-based genome sequencing of wild and domesticated barley, including ancient samples, to reveal a complex mosaic ancestry involving multiple wild populations, gene flow, and regional divergence, supporting a protracted, polycentric domestication process that continues to shape modern barley diversity.
Researchers from Stanford and the Arc Institute have used AI to design and successfully produce viruses that target bacteria, demonstrating the potential of AI in bioengineering, though ethical concerns about misuse remain.
Scientists have created the first viruses designed by AI, capable of infecting and killing E. coli bacteria, demonstrating AI's potential in designing complex biological systems and advancing biotechnological therapies, though further research is needed for creating entire living organisms.
Researchers discovered that Iberian harvester ant queens can produce two different species of ants from a single queen through a unique reproductive strategy involving cloning and hybridization, revealing a new mode of reproduction called xenoparity and providing insights into ant evolution and cloning mechanisms.
Scientists have confirmed that the Atlas blue butterfly has the highest number of chromosomes in the animal kingdom, with 229 pairs, a result of rapid chromosomal splitting over 3 million years, which may enhance genetic diversity and adaptability, though it also presents potential vulnerabilities amid environmental threats.