A study claiming the creation of a room-temperature superconducting material has been retracted by scientific journal Nature after Chinese researchers raised doubts about its validity. The paper, published earlier this year, gained widespread attention but was found to have manipulated data. The retraction raises questions about the initial claims and the scientific rigor behind them. Room-temperature superconductors are highly sought after for their potential applications in various fields.
Scientists have made a groundbreaking discovery by observing two bacteriophage viruses, one being a satellite virus, attaching to each other. This is the first time such an event has been observed, as satellite viruses typically depend on helper viruses for replication. The attachment occurred at the 'neck' of the helper virus, where its outer shell connects to its tail. The discovery was made using an electron microscope, and the findings were published in the Journal of the International Society for Microbial Ecology.
A beginner in CNC woodworking successfully replicated an original Game Boy case using walnut wood, utilizing nine different tools to reproduce the details of the injection-molded plastic case. The top and bottom shells were milled from both sides, requiring registration tricks and fixturing techniques. The front face lettering was milled out and filled with white spray paint, creating a beautiful contrast with the dark wood. While some challenges arose due to wood's limitations compared to plastic, the final result is a stunning and unique wooden Game Boy.
Researchers have developed a method called enhanced electric fluorescent in situ hybridization (EEL FISH) to detect the expression levels of hundreds of genes in tissue. However, conveying all the pertinent details of this complex technique in the methods section of a research article can be challenging. To overcome this limitation, step-by-step protocols can be provided to make the procedure easier to follow and implement. Platforms such as Protocols.io and OpenWetWare.org offer a forum for questions and comments, allowing for post-publication updates and long-term support. Communicating common pitfalls, documenting key steps with pictures or videos, and defining "obvious" steps can also enhance the accessibility and transparency of methods, making them more useful for replication and scientific research.
A new study in mice has found that the Omicron BA.5 variant of SARS-CoV-2 is more virulent and replicates faster than its predecessors. The study, published in Science Advances, used genetically modified mice to compare different subvariants of Omicron and found that BA.5 caused more severe illness and death, likely due to its ability to rapidly replicate early during infection. This study provides a valuable animal model for studying the new Omicron variants and understanding their behavior, as previous animal models did not exhibit illness with other variants. The findings suggest that targeting cytokines with drugs could potentially lessen symptoms and provide a treatment option.
Several research teams have disputed the findings of three high-profile studies that claimed tumors are filled with microbes, stating that they were unable to replicate the results and suggesting that the microbes were either mirages or the result of contamination. The authors of the original studies defended their data and pointed to more recent studies that support their conclusions. This controversy highlights the challenges of deciphering the true nature of tumor microbes and the growing pains of a promising field. While the debate continues, experts agree that microbes play a role in cancer, but the field is still searching for accurate tools and standards.
Scientists have determined that LK-99, a compound of copper, lead, phosphorus, and oxygen, is not a superconductor as previously claimed. The material's properties, including levitation and drops in electrical resistivity, were found to be the result of impurities, particularly copper sulfide. Replication efforts by various research teams have failed to observe room-temperature superconductivity in LK-99. The conclusion highlights the importance of careful analysis and the need for pure samples in studying material properties.
A group of creators has built an open-source replica of the Antikythera Mechanism, a 2000-year-old device considered one of the most important archaeological discoveries. The replica incorporates modern technology such as 3D printers and laser cutters, with some upgrades and changes to accommodate building in a modern workshop. The designs and schematics are open source, allowing for modifications, and various parts will be available for sale. While the ancient Greeks lacked the cosmological understanding to make the machine accurate for two thousand years, the replica remains a fascinating build, with ongoing discoveries about its functionality.
Researchers at Nanjing University attempted to replicate a paper claiming to have created a compound that superconducts at room temperature and moderate pressures. Despite producing the same chemical, the team saw no sign of superconductivity, even at extremely low temperatures. The original research came from a lab that had an earlier paper on superconductivity retracted, and the failure to replicate will raise further questions about the original claims. The rapid publication of this report should put pressure on the original lab to cooperate and sort out any differences that might explain the lack of replication.