All articles tagged with #drug delivery
A new implant called TAR-200 has shown promising results in a phase 2 trial, eliminating tumors in 82% of high-risk bladder cancer patients resistant to previous treatments, with most tumors disappearing within three months and many patients remaining cancer-free after a year, offering a potentially safer and more effective alternative to traditional therapies.
LaMar Cook, a former deputy director for the governor’s regional office in Springfield, was arraigned on charges of cocaine trafficking, gun possession without a license, and driving without a license after receiving a large drug delivery at the state building.
A study from Texas Tech found that the blood-brain barrier remains largely intact in a common mouse model of Alzheimer's, challenging previous beliefs that the disease causes widespread BBB leakiness, which has implications for drug delivery strategies.
Cambridge researchers have developed a pH-sensitive gel that can detect inflammation in joints and release anti-inflammatory drugs precisely where needed, potentially revolutionizing arthritis treatment by reducing side effects and improving efficacy, though clinical trials are still required.
University scientists in Chicago have developed a new nanostructure called LNP-SNA that triples CRISPR's ability to enter cells, significantly improving gene editing efficiency and safety, which could enhance treatments for genetic diseases.
Scientists at Northwestern University developed lipid nanoparticle spherical nucleic acids (LNP-SNAs) that significantly improve CRISPR delivery into cells, tripling gene-editing efficiency, reducing toxicity, and enhancing the potential for safer genetic medicines.
Scientists are exploring the use of pollen grains, transformed into a versatile microgel, for eco-friendly applications such as sustainable paper, films, sponges, and drug delivery systems, offering a resource-efficient alternative to traditional materials.
A new slow-release drug system called TAR-200 has shown to eliminate bladder cancer in 82% of patients in a clinical trial, especially effective for those unresponsive to traditional therapies, with the potential for FDA approval and improved quality of life for patients.
Affidavits reveal details in a quadruple homicide case in Lake County, involving Austin Drummond and others, with evidence of drug-related activities and accessory after the fact by Dearrah Sanders.
Scientists from the University of South Australia have developed a biodegradable, long-acting injectable gel that delivers levodopa and carbidopa steadily over a week, potentially transforming Parkinson's treatment by reducing dosing frequency and improving patient compliance. The formulation has shown promising safety and effectiveness in lab tests, with plans for clinical trials and commercialization.
Researchers from the University of South Australia have developed a biodegradable, weekly injectable formulation of levodopa and carbidopa that could significantly improve Parkinson's disease treatment by maintaining steady drug levels, reducing pill burden, and enhancing patient adherence, with potential applications for other chronic diseases.
Polish scientists have developed electrospun polymer mats containing metronidazole for targeted, controlled drug delivery to wounds, offering a promising method for precise antibiotic application that minimizes systemic effects.
MIT researchers developed a once-a-week oral pill for schizophrenia that maintains consistent drug levels and controls symptoms effectively, potentially improving medication adherence and patient outcomes, with promising results from phase 3 clinical trials.
A Caltech-led team has developed bioresorbable acoustic microrobots (BAM) capable of targeted drug delivery within the body. These microrobots, made from a hydrogel, can navigate complex biofluids and release drugs precisely at tumor sites, as demonstrated in mice with bladder tumors. The microrobots incorporate magnetic nanoparticles for navigation and ultrasound imaging for real-time tracking. This innovation could revolutionize precision medicine by delivering therapeutic agents directly to specific sites, minimizing side effects and improving treatment efficacy.
Researchers at Mount Sinai have developed a novel blood-brain barrier-crossing conjugate (BCC) platform that uses γ-secretase-mediated transcytosis to deliver large therapeutic molecules into the brain. This system successfully silenced harmful genes linked to ALS and Alzheimer's in mouse models and human brain tissue, offering a promising new approach for treating neurological disorders. The BCC platform could revolutionize drug delivery to the central nervous system, overcoming a major challenge in brain research.