Polish scientists have developed electrospun polymer mats containing metronidazole for targeted, controlled drug delivery to wounds, offering a promising method for precise antibiotic application that minimizes systemic effects.
Studies suggest that the commonly prescribed antibiotic metronidazole may not be effective in treating acute diarrhea in dogs and could negatively impact the gut microbiome. Veterinarians are being urged to use antibiotics sparingly to combat drug resistance. Research indicates that a modified diet, including highly digestible foods and possibly probiotics, may be just as effective in resolving diarrhea. However, some practitioners still rely on antibiotics to satisfy demanding clients. The use of educational materials and delayed prescribing are suggested as alternatives to address client expectations. The efficacy of probiotics in treating diarrhea is still uncertain, but they are considered safer than antibiotics. Further research is needed to determine the most effective probiotic strains and their impact on the gut microbiome.