Tag

Crohns Disease

All articles tagged with #crohns disease

health5 days ago•42 min saved

ER dismissal, then rectal cancer: a Toronto model’s urgent cancer journey

Toronto model Jess Grossman, who lives with an ostomy after childhood Crohn’s disease and colon removal, says ER staff brushed off her persistent pelvic pain as endometriosis until a CT scan raised flags. After a biopsy, she was diagnosed with rectal cancer four weeks from the first symptoms and is undergoing eight rounds of chemotherapy (16 weeks total) to shrink the tumor before potential surgery to remove the rectal stump. She documents her journey online to raise awareness about colorectal cancer and the importance of early detection.

via Yahoo Lifestyle Canada|

#chemotherapy #crohns-disease #early-detection

health6 days ago•5 min saved

When Early Signs Are Overlooked: One Woman’s Crohn’s Journey and Ostomy Advocacy

Paula Sojo’s viral TikTok recounts years of dismissed symptoms before a severe Crohn’s diagnosis at 18, followed by surgeries including a proctocolectomy and a permanent ostomy; now in remission and using her platform and her Osto•me Fashion brand to raise awareness, empower ostomy wearers, and push for earlier detection in others.

via AOL.com|

#crohns-disease #health #misdiagnosis

health10 days ago•264 min saved

Stool biomarkers and meat intake may forewarn IBD flares, study suggests

A large UK study (PREdiCCt) of over 2,600 people with inflammatory bowel disease found that higher baseline fecal calprotectin, a noninvasive stool marker of gut inflammation, strongly predicted future flares even when patients were symptom-free—UC patients with elevated calprotectin faced about a 34% objective flare risk within 2 years vs ~11% with low levels. Habitual meat intake was linked to nearly double the risk of ulcerative colitis flares, while other dietary factors showed no consistent associations; there was no such meat-flare link for Crohn’s disease. The results point to a potential for biomarker- and diet‑guided, personalized IBD management, using stool tests plus dietary data to forecast relapses months ahead. However, the study is observational and cannot prove causation, and local validation may be needed before widespread adoption.

via AOL.com|

#crohns-disease #fecal-calprotectin #health

science22 days ago•7 min saved

Gut Microbes Employ Protein-Delivery Syringes to Rewire Human Immunity

Researchers showed that common gut bacteria have type III secretion systems that inject proteins into human cells, altering immune signaling (including NF-κB and cytokine responses); these interactions are enriched in Crohn’s disease microbiomes, suggesting commensals can actively shape inflammation and may help explain microbiome–disease links while guiding future therapies.

via SciTechDaily|

#bacterial-effector-proteins #crohns-disease #gut-microbiome

health1 month ago•1 min saved

Israeli Tech Promises Early Detection of Crohn’s and IBD Flare-Ups

Israeli researchers have developed innovative technologies, including genetically engineered bacteria and a wearable stress monitor, to detect inflammatory bowel disease flare-ups before symptoms appear, potentially enabling earlier intervention and improved management of the condition.

via VINnews|

#crohns-disease #genetically-engineered-bacteria #health

health2 months ago•3 min saved

Israeli Tech Predicts Crohn’s Flares Before They Start

Innovative Israeli technologies using engineered bacteria and wearable stress monitors aim to detect Crohn's disease flare-ups before symptoms appear, potentially transforming disease management by enabling earlier intervention and reducing complications.

via ynetnews|

#crohns-disease #early-detection #health

medicine3 months ago•112 min saved

Fibroblast Niches Drive Crohn’s Fistula Formation

This study uses spatial transcriptomics and single-cell analysis to uncover how specialized fibroblast niches, particularly FAS cells, contribute to the formation, progression, and persistence of Crohn's fistulae, highlighting their roles in tissue remodeling, immune regulation, and epithelial regeneration, with implications for targeted therapies.

via Nature|

#crohns-disease #fibroblasts #fistulae

health3 months ago•2 min saved

AI Unravels 25-Year Crohn’s Disease Mystery and Identifies Protective Proteins

Researchers at UC San Diego used AI and molecular biology to uncover how a gene called NOD2 influences macrophage behavior in Crohn's disease, revealing that a mutation disrupting the NOD2-girdin interaction leads to chronic inflammation, and paving the way for new treatments.

via ScienceDaily|

#ai #crohns-disease #girdin

health4 months ago•4 min saved

AI Unravels 25-Year Crohn’s Disease Mystery and Identifies Protective Proteins

UC San Diego researchers used AI and molecular biology to uncover how the NOD2 gene influences macrophage behavior in Crohn's disease, revealing that mutations disrupt the balance between inflammatory and healing macrophages, which contributes to the disease's development.

via SciTechDaily|

#ai-in-research #crohns-disease #gut-inflammation

health4 months ago•3 min saved

AI Unravels Crohn's Disease Mystery and Identifies Protective Proteins

UC San Diego researchers used AI and molecular biology to uncover how a mutation in the NOD2 gene disrupts the balance of inflammatory and healing macrophages in Crohn's disease, resolving a 25-year mystery and highlighting potential treatment avenues.

via Medical Xpress|

#ai #crohns-disease #gut-health

health4 months ago•5 min saved

AI-Driven Discovery of Targeted Antibiotics for Gut Bacteria and IBD

Researchers at MIT and McMaster University used AI, specifically DiffDock, to develop and understand a targeted antibiotic, enterololin, that treats gut bacteria linked to Crohn's disease with minimal impact on the microbiome, potentially revolutionizing treatment and reducing antimicrobial resistance.

via MIT News|

#ai-drug-discovery #antibiotics #crohns-disease

health5 months ago•4 min saved

Diet Types That Exacerbate IBD Symptoms

A study shows that pro-inflammatory diets can worsen IBD symptoms, with those consuming such diets being up to three times more likely to experience moderate to severe disease, emphasizing the importance of an anti-inflammatory diet for managing IBD.

via Medical News Today|

#crohns-disease #diet #health

health5 months ago•3 min saved

Understanding the Fundamentals of Inflammatory Bowel Disease

Inflammatory bowel disease (IBD), affecting up to 3.1 million adults in the U.S., is a chronic condition where the immune system attacks the intestines, causing inflammation and damage. Diagnosis involves medical history, physical exams, lab tests, and imaging like endoscopy or MRI. IBD differs from irritable bowel syndrome (IBS), which has similar symptoms but no underlying disease. Managing IBD requires a team approach to find effective medication and lifestyle strategies to prevent flare-ups and address related health issues.

via Lawrence Journal-World|

#crohns-disease #diagnosis #health

health1 year ago•2 min saved

Breakthrough Drug Brings Hope for Crohn's-Free Future

Researchers at the Francis Crick Institute in London have discovered a key driver of inflammatory bowel disease (IBD) and other immune disorders, potentially leading to new treatments using existing drugs. This breakthrough could significantly impact the lives of millions suffering from conditions like Crohn's disease and ulcerative colitis.

via The Mirror|

#crohns-disease #francis-crick-institute #health

health1 year ago•2 min saved

Scientists Discover Major Cause and Potential Treatment for Crohn's Disease

Scientists at the Francis Crick Institute and University College London have discovered a "gene desert" in DNA linked to Inflammatory Bowel Disease (IBD), including Crohn's Disease. This genetic weak spot in white blood cells, which release inflammation-causing cytokines, appears in 95% of IBD patients. The discovery could lead to new treatments, including the use of existing MEK inhibitor drugs to reduce inflammation, potentially improving the lives of millions affected by IBD.

via Futurism|

#crohns-disease #genetics #health