All articles tagged with #gut inflammation
UC San Diego researchers used AI and molecular biology to uncover how the NOD2 gene influences macrophage behavior in Crohn's disease, revealing that mutations disrupt the balance between inflammatory and healing macrophages, which contributes to the disease's development.
New research suggests a link between gut inflammation and Alzheimer's disease, with studies showing that Alzheimer's can be passed on to young mice through a transfer of gut microbes. People with Alzheimer's were found to have higher gut inflammation, which correlated with higher levels of amyloid plaque accumulation in their brains. Levels of calprotectin, a sign of inflammation, were higher in older patients and even more pronounced in those with Alzheimer's characteristic amyloid plaques. The study indicates that gut inflammation may play a role in the development of Alzheimer's, and researchers are now testing mice to see if diet changes associated with increased inflammation can trigger the rodent version of the disease.
A study by the University of Wisconsin School of Medicine and Public Health suggests a link between gut inflammation and changes in the brain, memory decline, and Alzheimer’s disease, with higher levels of calprotectin associated with increased amyloid plaque in the brain. The research indicates that gut inflammation may be linked to neurodegenerative diseases, and ongoing studies are exploring the potential causality and impact of gut health on Alzheimer’s pathology. The findings highlight the functional connection between the gut and brain and may lead to further research on interventions such as probiotics to improve gut inflammation and potentially prevent cognitive decline associated with Alzheimer’s disease.