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Drug Resistant Bacteria

All articles tagged with #drug resistant bacteria

science2 months ago

Chemists Find Hidden Antibiotic for Drug-Resistant Bacteria

Chemists from Warwick and Monash Universities discovered a new, potent antibiotic, pre-methylenomycin C lactone, hiding as an intermediate in the natural biosynthesis of methylenomycin A. This compound shows over 100 times greater activity against Gram-positive bacteria, including resistant strains like MRSA and VRE, and may offer a new approach to combat antimicrobial resistance. The next steps involve pre-clinical testing and further development.

via Phys.org|
#amr#antibiotic#drug-resistant-bacteria
health3 months ago

CDC Reports Surge in Dangerous, Antibiotic-Resistant 'Nightmare Bacteria' in the US

The CDC reports a nearly 70% increase in cases of drug-resistant 'nightmare bacteria' in the US from 2019 to 2023, driven mainly by bacteria with the NDM gene, which are difficult to treat and may lead to community spread, highlighting a concerning rise in antimicrobial resistance exacerbated by increased antibiotic use during the COVID-19 pandemic.

via WHIO-TV|
#antibiotic-resistance#cdc#drug-resistant-bacteria
health3 months ago

CDC Reports Nearly 70% Rise in Drug-Resistant 'Nightmare Bacteria' Cases in the US

The CDC reports a nearly 70% increase in cases of drug-resistant 'nightmare bacteria' in the U.S. from 2019 to 2023, driven mainly by bacteria with the NDM gene, which are difficult to treat and could lead to community spread and more chronic infections. The rise is partly attributed to increased antibiotic use during the COVID-19 pandemic, and the actual number of cases is likely underestimated due to limited testing.

via CBS News|
#antibiotic-resistance#cdc#drug-resistant-bacteria
science7 months ago

Scientists Uncover First New Antibiotic Class in Three Decades

Researchers at McMaster University have discovered a new class of antibiotic called lariocidin, which shows promise against drug-resistant bacteria by attacking bacteria in a novel way, offering hope in the fight against antimicrobial resistance. The molecule is produced by soil bacteria and has been shown to be effective, non-toxic, and resistant to existing resistance mechanisms, but further development is needed before it can be used clinically.

via SciTechDaily|
#antibiotics#antimicrobial-resistance#drug-resistant-bacteria
health1 year ago

"Rising Concern: Drug-Resistant Superbugs in Pet Dogs' Diarrhea"

A study has found that pet dogs with diarrhea may be shedding drug-resistant E. coli, posing a serious risk to their owners. The research revealed that 118 out of 135 E. coli strains found in fecal samples from pet dogs were resistant to at least one antimicrobial agent. This drug resistance could lead to severe infections in humans, as E. coli is a common cause of food poisoning and other illnesses. The findings highlight the potential for pet dogs to become reservoirs for drug-resistant and pathogenic E. coli, emphasizing the need for further research and precautions to prevent the spread of these bacteria.

via Newsweek|
#antibiotic-resistance#drug-resistant-bacteria#e-coli
science-and-technology2 years ago

"AI Unveils Promising Antibiotic Candidates, Discovered by MIT Researchers"

MIT researchers have used deep learning, a type of artificial intelligence, to identify a new class of compounds that can kill drug-resistant bacteria, specifically methicillin-resistant Staphylococcus aureus (MRSA). These compounds have shown low toxicity against human cells, making them promising candidates for new antibiotics. The researchers also developed a method to understand the basis of the deep learning model's predictions, which could aid in the design of more effective antibiotics. The study is part of the Antibiotics-AI Project at MIT, which aims to discover new classes of antibiotics against deadly bacteria.

via EurekAlert|
#ai#antibiotics#deep-learning
health2 years ago

Reviving an Overlooked Antibiotic: A Promising Solution for Resistant Infections

Researchers have discovered that Nourseothricin, an old antibiotic, could be effective against drug-resistant Gram-negative bacteria. Improved purification techniques have identified less toxic forms of the antibiotic, specifically Streptothricin-F, that show strong activity against these bacteria by inducing translation errors in the bacterial ribosome. This finding offers a unique approach to combating difficult-to-treat infections and could potentially provide a new strategy to fight against multidrug-resistant pathogens.

via SciTechDaily|
#antibiotics#drug-resistant-bacteria#gram-negative-bacteria
health2 years ago

AI-assisted discovery of new antibiotic to combat drug-resistant infections

Researchers have used artificial intelligence to identify a new antibiotic, abaucin, that can effectively suppress the growth of the drug-resistant bacteria Acinetobacter baumannii, commonly found in hospitals and medical offices. The AI algorithm was used to predict molecules that would neutralize the bacteria, and the potential antibiotic was discovered after evaluating 7,684 drugs and active ingredients. While the results need to be validated in larger studies, researchers believe the process used to identify the drug is an approach that can work in drug discovery.

via USA TODAY|
#antibiotic#artificial-intelligence#drug-resistant-bacteria
health2 years ago

AI discovers powerful antibiotic to combat superbug.

Researchers have discovered a new type of antibiotic using artificial intelligence that works against drug-resistant bacteria. The antibiotic, called abaucin, was found to control the growth of the superbug Acinetobacter baumanii without harming beneficial bacteria. The compound works by preventing components of the bacteria from traveling from inside the cell to its surface, and it only targets the problem pathogen, making it a narrowly targeted agent. The researchers hope that more antibiotics will work this precisely to prevent bacteria from becoming resistant in the first place.

via CNN|
#antibiotics#artificial-intelligence#drug-resistant-bacteria