All articles tagged with #metastasis
In mice, cancer cells acquire mitochondria from immune cells, weakening those cells and activating a type I interferon program in the cancer cells that promotes lymph‑node invasion. Blocking this pathway reduces spread, and the effect occurs even when the stolen mitochondria can’t produce ATP, indicating energy production isn’t required for this mechanism.
Many cancers can recur years after initial treatment due to dormant tumour cells that evade therapy and immune detection, with ongoing research aiming to understand and target these cells to prevent relapse.
The article discusses how inactivation of p53 promotes breast cancer metastasis to the brain by upregulating SCD1 and enhancing fatty acid metabolism, highlighting potential molecular targets for therapy.
Scientists at UMass Amherst have developed a nanoparticle-based vaccine that successfully prevents multiple aggressive cancers in mice, including melanoma, pancreatic, and breast cancers, by activating strong immune memory and targeting cancer-specific antigens, with potential for broad application in cancer prevention and treatment.
Joe Biden has completed a series of radiation treatments for an aggressive, metastatic prostate cancer, with ongoing assessments needed to determine if further treatment is necessary. The former president's health updates have raised public concern, but he appears to be making progress in his recovery.
Researchers at the University of Massachusetts Amherst have developed a nanoparticle-based 'super-vaccine' that has shown promising results in preventing and stopping the spread of breast, pancreatic, and melanoma cancers in mice, with potential for future human applications.
Researchers at UMass Amherst developed a nanoparticle-based 'super vaccine' that successfully prevents and fights aggressive cancers like melanoma, pancreatic, and breast cancer in mice, showing high efficacy in preventing tumor growth and metastasis, with potential for human application.
A study from MD Anderson Cancer Center found that the glucose-fructose mix in sugary drinks promotes metastasis in advanced colorectal cancer by activating the SORD enzyme, suggesting that reducing sugary drink intake and targeting SORD could help slow disease progression.
Consumption of sugary drinks containing glucose and fructose promotes colorectal cancer metastasis via activation of the enzyme SORD, which increases the NAD+/NADH ratio and activates the mevalonate pathway, thereby enhancing cancer cell motility and spread.
Scientists at Rockefeller University discovered that mitochondrial glutathione, transported by SLC25A39, plays a crucial role in enabling breast cancer cells to metastasize, not by acting as an antioxidant but by activating stress response pathways, with potential implications for future cancer therapies.
Research reveals that mitochondrial glutathione and its transporter SLC25A39 play a crucial role in breast cancer metastasis by activating stress response pathways, with potential implications for targeted therapies to prevent cancer spread.
Research suggests that excessive peanut consumption may promote cancer metastasis by increasing agglutinin levels, which interact with blood vessels and cytokines, potentially aiding cancer spread. While peanuts are generally healthy, cancer patients should consider moderation, especially in large quantities, to avoid possible risks. The study emphasizes the importance of portion control for those with advanced cancer, though it does not link peanuts to increased mortality.
Scientists have found that respiratory illnesses like Covid and the flu can reactivate dormant cancer cells, leading to increased risk of metastasis, especially in cancer survivors. The inflammatory response, particularly the release of interleukin-6, appears to awaken these cells, which can then proliferate rapidly. Population studies support these findings, suggesting that respiratory infections may increase the risk of cancer recurrence and metastasis, highlighting the importance of vaccination and precautions for cancer patients.,
Research suggests that common respiratory viruses like COVID-19 and influenza may reactivate dormant breast cancer cells in the lungs, increasing the risk of metastasis and death among survivors, highlighting the importance of infection prevention and further studies on vaccination.
A 55-year-old man with advanced lung cancer developed rare acrometastasis, causing swelling and destruction of finger and toe bones, which is often a late sign of widespread cancer and associated with poor prognosis. The case highlights the importance of recognizing unusual symptoms as potential indicators of metastatic disease.