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Cancer Therapy

All articles tagged with #cancer therapy

Engineered Microbes Target Tumors by Colonizing Oxygen-Starved Cores
health-and-medicine1 day ago

Engineered Microbes Target Tumors by Colonizing Oxygen-Starved Cores

Researchers at the University of Waterloo are engineering Clostridium sporogenes bacteria to invade oxygen-poor tumor cores and consume nutrients from inside, potentially destroying tumors. They added an oxygen-tolerance gene and use quorum sensing to activate it only after enough bacteria accumulate, limiting safety risks. Next steps combine both features in a single strain and test in preclinical trials, showcasing interdisciplinary synthetic-biology cancer research.

New Research Solves 50-Year Tissue Regeneration Mystery
science2 months ago

New Research Solves 50-Year Tissue Regeneration Mystery

New research uncovers the molecular mechanisms behind tissue regeneration, identifying DARE and NARE cells that resist death and contribute to healing, with implications for understanding cancer resistance and improving therapies. The study highlights a motor protein that prevents apoptosis in DARE cells and reveals how resistance traits are inherited, potentially explaining tumor recurrence after radiation treatment.

Plant-Based Nutrients Enhance Immune Cells' Cancer-Fighting Power
health5 months ago

Plant-Based Nutrients Enhance Immune Cells' Cancer-Fighting Power

A study from the University of Chicago found that zeaxanthin, a plant-derived nutrient known for eye health, can enhance the immune system's ability to fight cancer by boosting T-cell activity, potentially improving the effectiveness of immunotherapies. The research suggests that dietary supplements like zeaxanthin could serve as accessible adjuncts to cancer treatment, though clinical trials are needed to confirm these benefits.

Bacteria-Delivered Viruses Enhance Cancer Treatment
health6 months ago

Bacteria-Delivered Viruses Enhance Cancer Treatment

Researchers at Columbia Engineering have developed a novel cancer treatment platform called CAPPSID that uses tumor-seeking bacteria to deliver and activate cancer-killing viruses directly inside tumors, effectively bypassing the immune system and enhancing targeted therapy. The system employs Salmonella bacteria to carry the virus into tumors, where it is released to infect cancer cells, with safeguards to prevent spread outside the tumor. Validated in mice, this innovative approach aims to improve the safety and efficacy of bacterial and viral cancer therapies, with efforts underway to translate it into clinical applications.