All articles tagged with #3d genome mapping
Scientists have created a detailed 4D map of the human genome, revealing how its components interact over time in three dimensions, which could lead to advances in understanding gene regulation and developing new cancer therapies.
MIT researchers have developed a new technique called Region Capture Micro-C (RCMC) for mapping the 3D structure of the human genome with 100 times higher resolution than before, enabling them to observe previously unseen interactions between enhancers and promoters. This technique allows scientists to focus on specific genome segments of interest and could help researchers understand how genetic diseases arise and potentially develop new treatments. The researchers’ findings suggest that many genes interact with dozens of different regulatory elements, although further study is needed to determine which of those interactions are the most important to the regulation of a given gene.