
Artificial sweeteners tied to faster cognitive aging in large Brazilian study
A Neurology study of 12,772 Brazilian adults over ~8 years found that higher intake of six common sugar substitutes (aspartame, saccharin, acesulfame-K, erythritol, sorbitol, xylitol; tagatose was the exception) is associated with faster cognitive decline, with the highest-intake group showing about 62% faster global decline (roughly 1.6 years of aging) and notable drops in memory and verbal fluency; the link is correlational, not proven causation, and potential mechanisms include toxic metabolites and brain inflammation. Sugar substitutes remain common in ultraprocessed foods, so moderation rather than complete avoidance is advised.













