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Ace2

All articles tagged with #ace2

"Revolutionizing Disease Research: Mouse Genome Rewriting Unlocks New Disease Models"

Originally Published 2 years ago — by Nature.com

Scientists have developed a novel mammalian genome writing method called mSwAP-In, which allows for large-scale, scarless, and iterative genome writing in mouse embryonic stem cells. Using this method, they successfully engineered a synthetic version of the Trp53 gene and fully humanized the ACE2 gene in mouse models. The humanized ACE2 mice were susceptible to SARS-CoV-2 infection and exhibited a more accurate representation of COVID-19 pathology compared to existing transgenic models. This genome writing technique has the potential to bridge human-mouse evolutionary gaps and improve our understanding of human diseases.

health science-and-technology ace2 covid-19 genetic-engineering genome-synthesis mouse-models science-and-technology

The Link Between Blood Type and COVID-19 Severity

Originally Published 2 years ago — by CNET

Studies have shown a correlation between blood type and COVID-19 infection risk, with blood group A being more susceptible and blood group O being somewhat protective. A new study published in the journal Blood provides evidence that the SARS-CoV-2 virus preferentially binds to the surface proteins associated with blood group A, enhancing its ability to enter cells. However, it's important to note that blood type is just one of many factors that contribute to infection risk, and precautions such as vaccination, wearing masks, and maintaining good ventilation should be taken regardless of blood type.

health health ace2 blood-type covid-19 health infection-risk sars-cov-2