Scientists have discovered a specific group of neurons in the brainstem that are active in chronic pain and produce a molecule called neuropeptide Y (NPY) that acts as a natural painkiller, opening potential pathways for new pain treatments.
Scientists have identified a specific group of neurons in the brainstem's parabrachial nucleus that are activated during chronic pain and produce a molecule, neuropeptide Y (NPY), which acts as a natural painkiller. This discovery suggests potential for developing new pain treatments that activate this molecule, offering hope for safer alternatives to opioids.
Chronic stress combined with a high-calorie diet can lead to excessive eating and weight gain, according to a study by researchers from the Garvan Institute of Medical Research in Sydney. The study found that stress suppresses the brain's natural response to satiety, leading to continuous reward signals that promote the consumption of highly palatable food. The molecule NPY, produced by the brain in response to stress, was identified as a key player in this process. The study emphasizes the importance of maintaining a healthy diet during times of stress to prevent excessive eating.