Tag

Knee Osteoarthritis

All articles tagged with #knee osteoarthritis

Consistency Over Intensity: Exercise Eases Osteoarthritis Pain, But Benefits Vary
health7 days ago

Consistency Over Intensity: Exercise Eases Osteoarthritis Pain, But Benefits Vary

A large umbrella review of systematic reviews and new trials finds that exercise modestly reduces pain in knee, hip, and hand osteoarthritis (about 6–12 on a 100-point scale) but often does not improve function more than doing nothing or placebo; exercise can be as effective as NSAIDs for knee/hip pain and is usually less effective than total joint replacement for pain and function. Limitations include lumping all exercise types together, not distinguishing supervised vs. unsupervised training, short study durations (~12 weeks), and not accounting for total weekly dose. Despite these caveats, regular exercise likely offers meaningful pain relief and broad health benefits, with long-term adherence and a target around 150 minutes of moderate activity per week providing the greatest gains; the best approach is the activity you can maintain consistently.

Top Exercises to Alleviate Knee Osteoarthritis Pain
health4 months ago

Top Exercises to Alleviate Knee Osteoarthritis Pain

A comprehensive review suggests that aerobic exercises like walking, cycling, and swimming are most effective for reducing pain and improving function in people with knee osteoarthritis, with other exercise types offering additional benefits. Regular aerobic activity is recommended as a primary treatment, but individuals should consult their doctors before starting new routines.

New Non-Invasive Treatments Offer Hope for Arthritis and Joint Pain Relief
health4 months ago

New Non-Invasive Treatments Offer Hope for Arthritis and Joint Pain Relief

A Korean clinical trial found that low-dose radiation therapy, particularly at 3 Gy, can significantly reduce pain and improve mobility in patients with mild to moderate knee osteoarthritis, offering a safe alternative to traditional treatments with minimal side effects, and highlighting the need for placebo-controlled studies in this area.

Obesity Drug Ozempic Offers Hope for Knee Osteoarthritis Relief
health1 year ago

Obesity Drug Ozempic Offers Hope for Knee Osteoarthritis Relief

A phase 3 clinical trial has shown that semaglutide, known as Ozempic for diabetes and Wegovy for weight loss, significantly reduces knee osteoarthritis pain and aids in weight loss. The study, published in the New England Journal of Medicine, found that a weekly dose of 2.4 mg of semaglutide outperformed placebos in pain relief and physical activity improvement. While promising, the study was funded by Novo Nordisk, the drug's manufacturer, and long-term use may be costly and challenging.

"Study: Knee Pain Accelerates Brain Aging"
health1 year ago

"Study: Knee Pain Accelerates Brain Aging"

A new study published in Nature Mental Health reveals a startling link between chronic knee pain, particularly from knee osteoarthritis (KOA), and accelerated brain aging. Researchers found that individuals with KOA exhibited significantly more rapid brain aging, particularly in regions crucial for cognitive function, such as the hippocampus. The study also identified a specific gene, SLC39A8, as a shared link between KOA and accelerated brain aging, suggesting that inflammation may play a key role in this relationship. These findings underscore the need for early detection and intervention strategies for KOA, as well as a more holistic approach to pain management that considers the potential long-term impacts on brain health.

Stem cell transplantation: A pain-relieving solution for knee osteoarthritis
health2 years ago

Stem cell transplantation: A pain-relieving solution for knee osteoarthritis

Stem cell transplantation, specifically using stem cells from umbilical tissue or a person's own adipose fat, has been found to be an effective and safe treatment for knee osteoarthritis pain and loss of function, according to a meta-analysis of 16 studies involving 875 patients. The analysis showed that all stem cell treatments resulted in a significant decrease in knee pain starting at three months of treatment. Knee osteoarthritis affects millions of people worldwide, and stem cell therapy offers promising potential for alleviating symptoms and improving joint function. However, further research is needed to standardize treatment protocols and evaluate long-term efficacy and safety.

health2 years ago

GLP-1 RA Drugs: A Promising Solution for Knee OA Pain and Progression

Glucagon-like peptide-1 receptor agonists (GLP-1 RA) drugs, such as liraglutide and semaglutide, which are approved for weight loss and type 2 diabetes, may have potential as disease-modifying treatments for knee osteoarthritis (KOA). Recent studies have shown promising results, with weight loss being a recommended treatment for KOA. However, the lack of pain relief in a phase 4 trial may be due to the trial design. Further research is needed to understand the disease-modifying effects of GLP-1 RA drugs in KOA patients. Several ongoing trials are investigating the efficacy of GLP-1 RA drugs in treating KOA.