All articles tagged with #epigenetic clocks
A study published in Aging suggests that higher blood levels of theobromine, a compound found in dark chocolate and smaller amounts in coffee, are associated with slower cellular aging as measured by epigenetic clocks, though causality and optimal intake levels remain unclear.
A recent study shows that theobromine, a compound found in chocolate and coffee, is linked to slower cellular aging, as measured by epigenetic clocks, suggesting potential health benefits from these foods.
A study finds that lifelong social advantages, from childhood to adulthood, can slow biological aging and reduce inflammation, highlighting the importance of sustained social connections for health and longevity.
A UVA study using epigenetic clocks on middle-aged twins found that faster biological aging predicts memory and cognitive decline, with socioeconomic factors amplifying this effect, highlighting the impact of poverty on health and aging.
A recent study shows that stressful and emotionally mixed relationships can accelerate biological aging, as measured by DNA methylation clocks, and negatively impact overall health. Managing social ties, setting boundaries, and fostering positive relationships may help mitigate these effects.
A new study suggests that young women who have been pregnant may experience accelerated biological aging compared to those who have never been pregnant, with the age gap appearing to widen in those who have had multiple pregnancies. The research, conducted in the Philippines, used epigenetic clocks to assess biological age and found that each pregnancy was associated with about 4 to 4.5 months of biological aging. The study's findings may have been influenced by factors such as access to nutrition and healthcare, and more research is needed to understand the impact of pregnancy on aging. The study could potentially inform future treatments to prevent or reverse accelerated aging related to pregnancy.
A study by Columbia University Mailman School of Public Health suggests that each pregnancy during early adulthood can add two to three months to a woman's biological ageing process, as determined by studying their 'epigenetic clocks'. This effect was not observed in men, indicating that there is something specific about pregnancy or breastfeeding that accelerates biological ageing. The study, published in the Proceedings of the National Academy of Sciences, focused on young women in late adolescence and highlights the potential long-term impacts of pregnancy on women's health, emphasizing the importance of supporting new parents, especially young mothers.
Researchers at Brigham and Women’s Hospital have developed a new DNA clock, called CausAge, DamAge, and AdaptAge, that can more accurately predict biological aging and the effectiveness of anti-aging treatments by distinguishing between genetic factors that accelerate or decelerate the aging process. The clocks are based on DNA methylation, a process closely linked to aging, and were validated using data from large cohorts, showing correlations with health outcomes and longevity. This breakthrough may lead to better quantification of biological age and evaluation of aging interventions.
Scientists are using epigenetic clocks to measure biological age, a true marker of health, but the role of the immune system in this process is not fully understood. A new study by Dartmouth Cancer Center scientists reveals how different immune cells affect epigenetic clocks, shedding light on the relationship between immune cell composition and biological age. This research has significant implications for aging insights, health interventions, and targeted cancer treatments, potentially revolutionizing precision medicine and cancer treatment.
Scientists are working on quantifying a person's "biological age" by examining their cellular health instead of their chronological age. Some companies offer direct-to-consumer blood tests that analyze epigenetic changes to calculate biological age, but experts caution that these tests are not yet reliable for individuals and are more suited for research purposes. The results can vary between different tests and it is unclear how to interpret or reverse the biological age. Other companies offer blood marker tests as a proxy for biological age, but their accuracy in tracking biological age is still debated. While the concept is intriguing, experts advise caution in interpreting and relying on these tests.
This article explores the concept of adaptation in aging, focusing on cellular senescence, epigenetic clocks, and stem cell alterations. It discusses the role of programmed cell death, DNA damage response, and wound healing in the aging process. The authors highlight the importance of senescent cells and their clearance, as well as the interplay between senescent cells and immune surveillance. The article also discusses the impact of oxidative stress, collagen fragmentation, and changes in extracellular matrix components on aging. Overall, the article provides insights into the mechanisms underlying adaptation and cellular changes during aging.
Depressive symptoms and living in deprived urban neighborhoods were found to be independently associated with accelerated biological aging, according to a new study. The research utilized DNA methylation-based epigenetic clocks to estimate biological age and found premature aging in individuals facing these circumstances. The study also found a connection between higher neighborhood deprivation and an increased risk of death. The influence of depression on premature aging seemed unrelated to neighborhood deprivation, suggesting different underlying mechanisms.