tldrdaily.news logo
Tag

Central Nervous System

All articles tagged with #central nervous system

neuroscience1 year ago

"Creation of Early Human Central Nervous System Model Using Stem Cells"

Researchers have developed a groundbreaking 3D human organoid system that accurately models the early stages of the human central nervous system (CNS) using patient-derived stem cells, offering new possibilities for studying human brain development and diseases. This comprehensive model simulates the development of the brain and spinal cord, potentially leading to personalized treatment strategies for neurological and neuropsychiatric disorders. The innovation provides a unique platform for understanding the intricacies of the human CNS and its disorders, surpassing the capabilities of previous models.

via Neuroscience News|
#central-nervous-system#human-brain-development#neurological-disorders
neuroscience1 year ago

"Uncovering Direct Connections: Brain's Interface with Surrounding Environment and Waste Disposal"

Researchers have identified direct connections between the dura and the brain, shedding light on the structural and functional features of central nervous system lymphatic vessels. The study provides evidence of dural sinuses serving as a neuroimmune interface and highlights the role of meningeal lymphatic drainage circuits in regulating CNS lymphatic drainage and neuroinflammation. Additionally, the findings reveal the involvement of meningeal lymphatic vessels in regulating various neurological processes, including cognitive impairment, anxiety-like behavior, and immune responses in the central nervous system.

via Nature.com|
#brain#central-nervous-system#dura
science2 years ago

"Unveiling the Neuroprotective Power of Astrocyte Reactivity: The Molecular Switch"

Researchers have discovered a molecular switch that regulates the reactivity of astrocytes, a type of brain cell, which can have neurotoxic or neuroprotective effects on the central nervous system. The study found that injured white matter astrocytes can differentiate into two distinct reactive populations, with neuroprotective astrocytes inhibiting microglial activation and promoting cell survival. By targeting this molecular switch, it may be possible to develop new treatments for conditions such as glaucoma and optic neuropathies.

via Nature.com|
#astrocytes#central-nervous-system#glaucoma
science2 years ago

Ancient Brain Regulatory Program Discovered Preceding Central Nervous System Evolution

New research suggests that the gene mechanisms involved in brain development actually predate the evolution of the central nervous system. The study focused on Nematostella vectensis, a starlet sea anemone, and found that the gene programs responsible for patterning the brain were also present in the anemone's simpler neural net. This suggests that nature borrowed the blueprints for building brains from simpler creatures that predate humans and other animals on the evolutionary timeline. The findings challenge the notion of all brains being homologous, descended from a common ancestor, and support the idea that brain development evolved through the co-option of existing gene programs.

via Phys.org|
#brain-development#central-nervous-system#evolution
health2 years ago

Neurological Migration: Covid Virus Infects Brain via Neurons

A study conducted by researchers from the Institut Pasteur and Universite Paris Cite in France has shown that different variants of SARS-CoV-2, including the original strain from Wuhan and the Gamma, Delta, and Omicron/BA.1 variants, can infect the central nervous system and migrate within neurons. The study confirmed that the virus can infect human neurons in vitro and spread through axons, the nerve cell projections. The researchers also found that the virus can enter the olfactory bulb, a structure in the cranial cavity responsible for processing olfactory information. The study suggests that neuronal infection and anosmia (loss of smell) may be unrelated phenomena, and even asymptomatic infections could involve the spread of the virus in the nervous system.

via Business Insider India|
#central-nervous-system#covid-19#health
health2 years ago

Defense Department Discovers Potential Cure for Rabies

Researchers from the Uniformed Services University of the Health Sciences have made progress in finding a cure for rabies, a fatal disease that causes inflammation of the brain and spinal cord. The study, conducted on mice, has shown promising results in neutralizing the virus. Rabies is a concern for the U.S. military as troops often operate in areas where the virus is present in wild dogs. If successful, this research could have broader implications for treating other viral diseases that target the central nervous system.

via Military Times|
#central-nervous-system#cure#health
science-and-technology2 years ago

"Mesmerizing Time-Lapse Reveals Neuronal Fireworks Inside Chick Embryo"

A mesmerizing time-lapse video captured by a postdoctoral fellow at the University of Zurich shows developing neurons in a chick embryo connecting to the opposite side of the central nervous system. The video, which won the 2023 Nikon Small World in Motion Video Competition, reveals the intricate behavior of nerve cells as they shoot across the embryo. The researcher hopes that this work will contribute to a better understanding of neurodevelopmental disorders and improve our knowledge of how the brain develops.

via Yahoo Life|
#central-nervous-system#chick-embryo#neurodevelopmental-disorders
health2 years ago

Link Found Between Bacterial Toxin and Multiple Sclerosis

A specific toxin-producing gut bacteria, epsilon toxin-producing Clostridium perfringens, may be responsible for triggering the onset of multiple sclerosis (MS) and ongoing disease activity, according to a new study. The study identifies the bacteria in unusually high abundance within the gut microbiome of people with MS. Epsilon toxin opens the blood vessels of the brain allowing inflammatory cells to gain access to the central nervous system and cause demyelination characteristic of MS.

via Neuroscience News|
#central-nervous-system#demyelination#gut-bacteria