Tag

Amygdala

All articles tagged with #amygdala

Amygdala Shifts Between Learning Strategies to Enable Flexible Choices
science3 days ago

Amygdala Shifts Between Learning Strategies to Enable Flexible Choices

New Dartmouth-led research reframes the amygdala as a dynamic arbiter that toggles between action-based and stimulus-based learning under uncertainty, promoting flexible decision-making. When the amygdala is damaged, arbitration becomes random and behavior locks into rigid action-based patterns. The findings offer a potential path for treating phobias and anxiety by encouraging action-based exploration over stimulus-driven fear, and pave the way for further studies on how the amygdala coordinates with prefrontal circuits to guide learning.

The rare condition that eliminates fear sensation
science5 months ago

The rare condition that eliminates fear sensation

Some rare individuals, like Jordy Cernik and SM, lack the ability to feel fear due to damage or mutation affecting the amygdala, a brain region involved in processing fear, revealing that fear responses are complex and can be specific to external or internal threats, with implications for understanding survival and modern stress.

Amygdala-Liver Signaling Regulates Stress-Induced Blood Sugar Changes
science5 months ago

Amygdala-Liver Signaling Regulates Stress-Induced Blood Sugar Changes

The study uncovers a novel amygdala–liver pathway that rapidly regulates blood glucose during stress independently of traditional hormonal systems, involving specific neurons in the medial amygdala projecting to the hypothalamus and liver, which are activated by stress and control hepatic glucose production. Repeated stress disrupts this circuit, linking chronic stress to metabolic disorders like type 2 diabetes.

Thyroid Hormones Found Crucial in Fear Memory Formation
science8 months ago

Thyroid Hormones Found Crucial in Fear Memory Formation

A study reveals that thyroid hormones in the brain, particularly in the amygdala, play a crucial role in fear memory formation, with potential implications for treating trauma-related disorders like PTSD. Enhancing or blocking thyroid hormone activity affects fear memory strength, and these effects are linked to specific gene regulation, suggesting new avenues for therapeutic intervention.