"Vitamin A's Crucial Role in Stem Cell Biology, Wound Healing, and Cancer Development"
Originally Published 1 year ago — by Phys.org
New research suggests that retinoic acid, the biologically active form of Vitamin A, plays a crucial role in regulating lineage plasticity in stem cells, particularly in the context of wound repair and hair regeneration. The study found that retinoic acid is essential for stem cells to exit lineage plasticity and differentiate into hair or epidermal cells, with implications for understanding skin and hair disorders, as well as potential applications in cancer treatment. The findings shed light on the complex role of Vitamin A in orchestrating stem cell lineage choices and have the potential to transform the study of hair biology and improve prognoses for certain types of cancer.
