Tag

Pathogen Defense

All articles tagged with #pathogen defense

"Reviving Ancient Molecules: Unearthing Antibiotic Potential from Neanderthals and Denisovans"

Originally Published 2 years ago — by IFLScience

Featured image for "Reviving Ancient Molecules: Unearthing Antibiotic Potential from Neanderthals and Denisovans"
Source: IFLScience

Scientists have successfully recreated molecules produced by extinct branches of the human family, such as Neanderthals and Denisovans, for the first time. This "molecular de-extinction" could help us understand our long-lost relatives and potentially fight pathogens to which they may have been immune. By studying the proteins coded in the DNA of our nearest relatives, researchers hope to gain insights into their immune systems and develop new ways to combat diseases in the modern world.

Uncovering an Ancient Wound Repair Mechanism.

Originally Published 2 years ago — by Phys.org

Featured image for Uncovering an Ancient Wound Repair Mechanism.
Source: Phys.org

Researchers from Rockefeller University have discovered a new mechanism for wound repair that is distinct from the classical pathway triggered by pathogens. The mechanism is led by interleukin-24 (IL24), which is induced in skin epithelial stem cells at the wound edge. The wound-induced IL24 signaling cascade is independent of germs and is activated by hypoxia caused by blood vessel disruption and scab formation. The researchers found that without IL24 functionality, the healing process was sluggish and delayed. They speculate that IL24 might be involved in the injury response in other body organs featuring epithelial layers.