Tag

Tumors

All articles tagged with #tumors

Inside-Out Attack: Engineered Bacteria Target Tumors
science2 days ago

Inside-Out Attack: Engineered Bacteria Target Tumors

University of Waterloo scientists are engineering Clostridium sporogenes to colonize the oxygen-free centers of tumors and consume nutrients, effectively eating tumors from the inside out. By adding an oxygen-tolerance gene from a related bacterium, they hope the bacteria can survive near the tumor exterior, while a quorum-sensing system activates the gene only when enough bacteria are present, preventing growth in oxygen-rich areas such as the bloodstream. The team plans pre-clinical trials testing this approach, though substantial work remains before any clinical use.

Prenatal Glyphosate Exposure Linked to Cancer Risk in Rats
environmental-health9 months ago

Prenatal Glyphosate Exposure Linked to Cancer Risk in Rats

A long-term study on Sprague–Dawley rats found that exposure to glyphosate and glyphosate-based herbicides at levels similar to EU safety limits increased the incidence of multiple benign and malignant tumors, including leukemia, skin, liver, thyroid, and nerve tumors, supporting the classification of glyphosate as a probable carcinogen based on experimental evidence.

"Rare Disease Causes Woman to Develop Thousands of Tumors All Over Her Body"
health1 year ago

"Rare Disease Causes Woman to Develop Thousands of Tumors All Over Her Body"

Charmaine Sahadeo, 42, from Trinidad, suffers from NF-1 neurofibromatosis, a rare condition causing thousands of tumors to grow all over her body, obstructing her ability to breathe, eat, talk, and walk. After traveling 4,000 miles for surgery with Dr. Ryan Osborne in Los Angeles, she underwent 60 hours of operations to remove hundreds of tumors, significantly improving her quality of life. NF-1 neurofibromatosis affects approximately one in 3,000 people worldwide and can lead to various health complications.

Uncovering Cancer's Manipulation of the Nervous System
health2 years ago

Uncovering Cancer's Manipulation of the Nervous System

Cancer cells, including brain tumors, have been found to communicate and interact with the nervous system, using it to survive, grow, and spread. This emerging field of cancer neuroscience has revealed that cancer cells can form direct connections with neurons, influence the immune system, and even reshape functional circuits in the brain. Researchers are exploring therapies that target these interactions, including repurposing existing drugs to disrupt neuronal communication and potentially improve cancer treatment outcomes.

Surviving Tumour Invasion: From Forehead Tumours to a Huge Dent
health2 years ago

Surviving Tumour Invasion: From Forehead Tumours to a Huge Dent

Ido Simyoni, a man from New York, underwent surgery to remove multiple tumors in his forehead caused by fibrous dysplasia, a condition that causes scar-like tissue to form instead of normal bone. The surgery left him with a large dent in his forehead, but he is grateful to be alive. Ido had been living with the condition since he was 15 years old and had previously undergone surgery at 17 to remove a tumor near his brain. After experiencing swelling last year, he underwent two more surgeries to remove a tumor and replace his forehead bone. Despite the challenges, Ido is now on the mend and plans to run all six World Major Marathons in 2024.

Unveiling the Role of a Novel Hormone in Tumour-Induced Kidney Dysfunction
medical-research2 years ago

Unveiling the Role of a Novel Hormone in Tumour-Induced Kidney Dysfunction

Researchers have discovered a novel antidiuretic hormone that regulates tumor-induced renal dysfunction. Using Drosophila as a model, the study found that tumors release a hormone called Ion Transport Peptide (ITP), which inhibits fluid secretion in the Malpighian tubules, leading to impaired kidney function. The researchers also identified the receptor for ITP and demonstrated its role in regulating water homeostasis. This study provides insights into the mechanisms underlying tumor-induced renal dysfunction and may lead to the development of new therapeutic strategies.

From Chickenpox Scar to Tumors: A Woman's Inspiring Journey of Resilience and Defying Trolls
health2 years ago

From Chickenpox Scar to Tumors: A Woman's Inspiring Journey of Resilience and Defying Trolls

Mercedes Christensen, a 52-year-old mother from Idaho, has spoken out against trolls who have criticized her for passing on her rare genetic condition, neurofibromatosis type 1 (NF1), to her children. NF1 causes benign tumors to form under the skin and along the nerves. Christensen was diagnosed at 19 and initially had only a few tumors, but after giving birth to her youngest daughter, her condition worsened rapidly. Her daughters, now 27 and 24, were also diagnosed with NF1. Despite facing negativity and guilt, Christensen has chosen to embrace self-acceptance and not respond to negativity with negativity.

Breakthrough pancreatic cancer treatment shows promise in eradicating tumors and stopping spread.
health2 years ago

Breakthrough pancreatic cancer treatment shows promise in eradicating tumors and stopping spread.

Researchers from the University of Colorado Cancer Center have found that combining radiation and immunotherapy could be the key to eliminating pancreatic tumors while stopping the cancer from spreading. The study, carried out with animal models, is the first time immunotherapy has been used with radiation therapy to target pancreatic cancer tumors. Clinical trials haven’t started for humans, but the results have been encouraging so far. Pancreatic cancer is the third-deadliest cancer in the US, and the American Cancer Society predicts 64,000 people will be diagnosed with pancreatic cancer this year, and 50,000 will die from it.

Woman battles over 100 tumors in her body.
health2 years ago

Woman battles over 100 tumors in her body.

Michele Holbrook, a Florida woman with schwannomatosis, a rare condition that causes the growth of small masses along nerves and in the skull, has more than 100 tumors in her body, causing debilitating pain. She has had to give up her active lifestyle and running due to the pain. There is no cure for the condition, and treatments are limited. Holbrook is an ambassador with Children's Tumor Foundation, where she works to spread awareness of the condition, particularly in children and young adults. She is willing to take an extra mile to fight for them.

Schwannomatosis: Woman's Body Harbors Over 100 Tumors.
health2 years ago

Schwannomatosis: Woman's Body Harbors Over 100 Tumors.

Michele Holbrook has been diagnosed with schwannomatosis, a rare genetic disorder that causes benign tumors to grow throughout the body. She has had over 100 tumors, with 13 removed so far. The pain can be excruciating, but she uses it to help younger generations with the same condition. Holbrook is an ambassador for the Children's Tumor Foundation and is raising money for research into neurofibromatosis. She encourages patients to register for clinical trials and to support the NF community.