New research reveals high levels of the Alzheimer's-associated protein p-tau217 in healthy newborns, suggesting it plays a crucial role in brain development rather than solely causing neurodegeneration, challenging existing assumptions and opening new avenues for understanding and treating Alzheimer's disease.
A recent study published in Nature Metabolism reveals that a seven-day water fast leads to significant weight loss and triggers whole-body protein level changes, making some organs operate more effectively. The research, conducted on 12 volunteers, showed that the body switches to using its own fat stores as fuel during fasting. While fasting has been linked to health benefits beyond weight loss, such as reducing signs of Alzheimer's and aging, it may not be suitable for individuals in ill health and should be done under medical supervision to avoid potential risks.
A new study published in Nature Metabolism reveals the effects of a 7-day water fast on the human body, showing significant weight loss and changes in whole-body protein levels that made some organs operate more effectively, including the supportive structure for neurons in the brain. While fasting can lead to weight loss and potential health benefits beyond weight loss, it may not be suitable for individuals in ill health. Diets that integrate fasting, like intermittent fasting, have been linked to various health outcomes, but it's important to seek medical advice before undertaking any fasting regimen.
Researchers have identified potential early warning signs of dementia by analyzing minute differences in the levels of specific proteins in blood, which could lead to significant implications for screening and early intervention. A study comparing plasma proteins in adults without dementia revealed common changes in the blood serum of those who later developed dementia, including Alzheimer's disease. Four specific proteins - GFAP, NEFL, GDF15, and LTBP2 - were consistently present in the plasma of patients who would be diagnosed with dementia. Higher levels of GFAP were associated with a 2.32 times higher likelihood of developing dementia, and changes in GFAP and NEFL levels were detected up to a decade before the onset of clear symptoms. This research could lead to the development of a simple blood test for predicting dementia risk, allowing for early interventions to slow down the disease's progress.