Tag

Opioids

All articles tagged with #opioids

Federal probe shadows Jim Irsay's death and its treatment questions
national1 month ago

Federal probe shadows Jim Irsay's death and its treatment questions

The death of Indianapolis Colts owner Jim Irsay is under federal investigation by the FBI and DEA, examining the circumstances of his May death at the Beverly Hills Hotel and the involvement of a California addiction specialist who treated him with opioids and ketamine; the death certificate cites cardiac arrest due to pneumonia with no autopsy, and the probe is in its early stages while the Colts say they have not been contacted by authorities.

health1 month ago

Trump Admin Slices $1.9B in Mental Health and Addiction Grants, Reshaping SAMHSA

The Trump administration terminated about 2,800 discretionary SAMHSA grants worth roughly $1.9 billion as of Jan. 13, aimed at realigning the agency’s portfolio toward innovative programs; the cuts threaten access to mental health and addiction services, complicate 2026 funding negotiations, and come amid SAMHSA staffing declines, with potential funding gaps if Congress does not act before Jan. 30.

Gene Therapy Targets Pain Circuits to Relieve Chronic Pain Without Addiction
science1 month ago

Gene Therapy Targets Pain Circuits to Relieve Chronic Pain Without Addiction

A preclinical CNS-targeted gene therapy dampens pain signals in specific brain circuits to relieve chronic pain while avoiding the brain reward pathways tied to addiction, using AI-guided imaging and animal models, with an off switch for long-lasting relief and moving toward clinical trials to help the roughly 50 million Americans affected by chronic pain.

Scientists Find Safer Method for Pain Relief Without Opioid Risks
health1 month ago

Scientists Find Safer Method for Pain Relief Without Opioid Risks

Scientists at USF Health have discovered new ways opioid receptors can function, potentially leading to pain medications that provide effective relief without the dangerous side effects like respiratory depression, by favoring a reverse signaling pathway. This research could pave the way for safer, non-addictive pain treatments and improve understanding of receptor mechanisms.